Evidence mapPaperPMID 37167271Full record

ArticleAmerican journal of physiology. Renal physiology2023

Male Akita mice develop signs of bladder underactivity independent of NLRP3 as a result of a decrease in neurotransmitter release from efferent neurons.

Francis M Hughes, Armand Allkanjari, Michael R Odom, Jack E Mulcrone, Huixia Jin, J Todd Purves

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Francis M HughesDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States.ORCID 0000-0003-3776-3653
Armand AllkanjariDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States.ORCID 0000-0002-4185-4200
Michael R OdomDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States.ORCID 0000-0003-2524-9825
Jack E MulcroneDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States.
Huixia JinDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States.ORCID 0000-0003-4645-2478
J Todd PurvesDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States.ORCID 0000-0001-9689-2047
Duke Medical Center · US

Funding

Duke KURe ProgramK12DK100024 · DUKE UNIVERSITY · 2025 to 2025
$762k
NIDDK NIH HHS K12 DK100024NIDDK NIH HHS R01 DK117890
6 · The paper itself

Abstract

Diabetic bladder dysfunction (DBD) is a prevalent diabetic complication that is recalcitrant to glucose control. Using the Akita mouse model (type 1) bred to be NLR family pyrin domain containing 3 (NLRP3)

Indexed as

HyperglycemiaUrologic DiseasesAnimalsFemaleInflammationMaleMiceNeurons, EfferentNLR Family, Pyrin Domain-Containing 3 ProteinUrinary BladderNLR Family, Pyrin Domain-Containing 3 Proteinbladdercomplicationsdiabetesinflammationurodynamics

Identifiers

PMID37167271
PMCPMC10292983
OpenAlexW4376224444

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.