ReviewHealthcare (Basel, Switzerland)2023
Impact of Clear Aligners versus Fixed Appliances on Periodontal Status of Patients Undergoing Orthodontic Treatment: A Systematic Review of Systematic Reviews.
Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07660809 (Comparison of Patient-Reported Comfort Between Supragingival and Juxtagingival Clear Aligner Trimming-Line Designs), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Patient-Reported Comfort Between Supragingival and Juxtagingival Clear Aligner Trimming-Line Designs: A Cross-Sectional, Within-Subject Split-Mouth Study
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Effects of clear aligners treatment in growing patients: a systematic review.Frontiers in oral health · 2024Pooled it
- Plaque removal efficacy of manual versus powered toothbrushes in patients with clear aligners: a single-brushing randomized controlled trial.BMC oral health · 2026Trial
- Tooth rotational control with varying attachment configurations in clear aligners under compromised periodontal ligament support: a finite element study.BMC oral health · 2026Article
- Difference in Occlusal Contacts Obtained with Conventional Orthodontic and Clear Aligner Therapy: A Pilot Study.Dentistry journal · 2026Article
- Clear Aligner Therapy and Marginal Edge Design: Clinical and Laboratory Evidence on Periodontal and Biological Outcomes-A Scoping Review.Dentistry journal · 2026Review
- Review
- Clear aligner therapy beyond esthetics: oral health, polymer materials, and the environmental cost of digital orthodontics.Frontiers in dental medicine · 2026Review
- Do treatment outcomes of clear aligners remain stable over time? A systematic review.Journal of orthodontic science · 2026Review
- Comparison of Low-Dose, Standard-Dose, and High-Definition CBCT Protocols for STL Reconstruction Accuracy in Digital Bone Scaffold Workflows.International journal of dentistry · 2026Article
- Duration-Dependent Caries Risk During Clear Aligner Therapy: A Retrospective Analysis.Biomimetics (Basel, Switzerland) · 2025Article
- Assessment and Evaluation of Oral Health in Orthodontic Patients: A Cross-Sectional Study.Cureus · 2025Article
- Micro- and Nanoplastics and the Oral Cavity: Implications for Oral and Systemic Health, Dental Practice, and the Environment-A Narrative Review.Journal of functional biomaterials · 2025Review
- Article
- Indications and limits of clear aligner therapy: an international modified Delphi consensus study.Progress in orthodontics · 2025Review
- Periodontal Microbial Profiles Across Periodontal Conditions in Pediatric Subjects: A Narrative Review.Microorganisms · 2025Review
- Biofilm Composition Changes During Orthodontic Clear Aligners Compared to Multibracket Appliances: A Systematic Review.Microorganisms · 2025Review
- Expert consensus on orthodontic treatment of patients with periodontal disease.International journal of oral science · 2025Review
- Periodontal Status and Herpesiviridae, Bacteria, and Fungi in Gingivitis and Periodontitis of Systemically Compromised Pediatric Subjects: A Systematic Review.Children (Basel, Switzerland) · 2025Review
- A Retrospective Study Regarding the Efficacy of NuvolaDiagnostics (Basel, Switzerland) · 2025Article
- Oral health in adolescents: periodontal inflammatory biomarkers during orthodontic clear aligner therapy.Clinical oral investigations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present umbrella review of four systematic reviews with meta-analysis aimed to assess whether clear aligners are associated with better periodontal conditions compared with fixed appliances in patients undergoing orthodontic treatment. The present study protocol was developed in accordance with the PRISMA statement before the literature search, data extraction, and analysis and was registered on PROSPERO (CRD42023401808). The question formulation, search, and study selection strategies were developed according to the PICO model. Systematic reviews with a meta-analysis published in English without date restriction were electronically searched across the Cochrane Library, Web of Science (Core Collection), Scopus, EMBASE, and MEDLINE/PubMed databases until 10 February 2023. An assessment of study quality was performed using the AMSTAR 2 tool. Differences in the PI, GI, and BOP in the short- and medium-term follow-ups, in the PPD in long-term follow-up, and the gingival recessions in the short-term follow-up were found between subjects with clear aligners and fixed appliances, revealing a slight tendency for clear aligners to be associated with healthier periodontal conditions. However, even if statistically significant, such differences would be negligible in a clinical environment. Therefore, the impact of orthodontic treatment with clear aligners and fixed appliances on periodontal health status should be considered comparable.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.