Evidence mapPaperPMID 37175010Full record

ArticleDiagnostics (Basel, Switzerland)2023

Comprehensive Genomic Profiling and Therapeutic Implications for Patients with Advanced Cancers: The Experience of an Academic Hospital.

Laure-Anne Teuwen, Evelyne Roets, Pieter D'Hoore, Patrick Pauwels, Hans Prenen

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Impact of Concordance between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the ROME Trial.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Laure-Anne TeuwenDepartment of Oncology, Antwerp University Hospital, Drie Eikenstraat 655, 2650 Edegem, Belgium.
Evelyne RoetsDepartment of Oncology, Antwerp University Hospital, Drie Eikenstraat 655, 2650 Edegem, Belgium.
Pieter D'HooreDepartment of Oncology, Antwerp University Hospital, Drie Eikenstraat 655, 2650 Edegem, Belgium.
Patrick PauwelsDepartment of Pathology, Antwerp University Hospital, Drie Eikenstraat 655, 2650 Edegem, Belgium.
Hans PrenenDepartment of Oncology, Antwerp University Hospital, Drie Eikenstraat 655, 2650 Edegem, Belgium.ORCID 0000-0001-8802-7352
Antwerp University Hospital · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-generation sequencing (NGS) can be used to detect tumor-specific genomic alterations. This retrospective single-center study aims to assess the application of an extensive NGS panel to identify actionable alterations and initiate matched targeted treatment for patients with advanced cancer. We analyzed genomic alterations in solid tumor biopsies from 464 patients with advanced cancer with the Foundation Medicine assay (FoundationOne

Indexed as

advanced cancergenomic profilingnext-generation sequencingOncoKB classificationtargeted therapy

Identifiers

PMID37175010
PMCPMC10177779
OpenAlexW4376630182

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.