Evidence map›Paper›PMID 37175137›Full record

ReviewMolecules (Basel, Switzerland)2023

Aptamers Targeting Membrane Proteins for Sensor and Diagnostic Applications.

Nilufer Kara, Nooraldeen Ayoub, Huseyin Ilgu, Dimitrios Fotiadis, Muslum Ilgu

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. DNA-modulated dimerization and oligomerization of cell membrane receptors.Chemical communications (Cambridge, England) · 2024
    Review
  9. Aptamers' Potential to Fill Therapeutic and Diagnostic Gaps.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Nilufer KaraDepartment of Biological Sciences, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0002-6618-379X
Nooraldeen AyoubDepartment of Biological Sciences, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0003-3146-242X
Huseyin IlguInstitute of Biochemistry and Molecular Medicine, University of Bern, CH-3012 Bern, Switzerland.ORCID 0000-0003-4550-4352
Dimitrios FotiadisInstitute of Biochemistry and Molecular Medicine, University of Bern, CH-3012 Bern, Switzerland.ORCID 0000-0001-9682-7931
Muslum IlguDepartment of Biological Sciences, Middle East Technical University, Ankara 06800, Turkey.ORCID 0000-0003-1558-462X
University of Bern · CHIowa State University · USMiddle East Technical University · TR

Funding

Swiss National Science Foundation 182895
6 · The paper itself

Abstract

Many biological processes (physiological or pathological) are relevant to membrane proteins (MPs), which account for almost 30% of the total of human proteins. As such, MPs can serve as predictive molecular biomarkers for disease diagnosis and prognosis. Indeed, cell surface MPs are an important class of attractive targets of the currently prescribed therapeutic drugs and diagnostic molecules used in disease detection. The oligonucleotides known as aptamers can be selected against a particular target with high affinity and selectivity by iterative rounds of in vitro library evolution, known as

Indexed as

Aptamers, NucleotideBiomarkersHumansLigandsMembrane ProteinsSELEX Aptamer TechniqueAptamers, NucleotideBiomarkersLigandsMembrane Proteinsaptamersaptasensorbiosensordiagnosticsmembrane proteinsSELEX

Identifiers

PMID37175137
PMCPMC10180177
OpenAlexW4367054553

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.