Evidence map›Paper›PMID 37175449›Full record

ArticleInternational journal of molecular sciences2023

Puerarin Alleviates H

Chenchen Lyu, Bao Yuan, Yu Meng, Shuai Cong, Haoyu Che, Xingyu Ji, Haoqi Wang, Chengzhen Chen, Xinwei Li, Hao Jiang and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Mechanism of Cinnamaldehyde in AlleviatingAnimals : an open access journal from MDPI · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Pulsatilla Saponin B4 Alleviates HAntioxidants (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chenchen LyuDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Bao YuanDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.ORCID 0000-0003-3490-0755
Yu MengDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Shuai CongDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Haoyu CheDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Xingyu JiDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Haoqi WangDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Chengzhen ChenDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.
Xinwei LiKey Laboratory of Zoonoses Research, College of Veterinary Medicine, Jilin University, Changchun 130062, China.
Hao JiangDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.ORCID 0000-0003-2008-6166
Jiabao ZhangDepartment of Laboratory Animals, Jilin Provincial Key Laboratory of Animal Model, Jilin University, Changchun 130062, China.ORCID 0000-0001-8533-4744

Funding

Jilin Provincial Science and Technology Program SXGJSF2017-6The Chinese Agricultural Science Research System CARS-37
6 · The paper itself

Abstract

During the perinatal period, the bovine mammary epithelial cells of dairy cows exhibit vigorous metabolism and produce large amounts of reactive oxygen species (ROS). The resulting redox balance disruption leads to oxidative stress, one of the main causes of mastitis. Puerarin (PUE) is a natural flavonoid in the root of PUE that has attracted extensive attention as a potential antioxidant. This study first investigated whether PUE could reduce oxidative damage and mastitis induced by hydrogen peroxide (H

Indexed as

AntioxidantsMastitisAnimalsCattleEpithelial CellsFemaleHumansHydrogen PeroxideInterleukin-6IsoflavonesLactationMilkOxidative StressPregnancyReactive Oxygen SpeciesAntioxidantsHydrogen PeroxideInterleukin-6IsoflavonespuerarinReactive Oxygen Speciesblood–milk barrierBMECsmastitisoxidative stresspuerarin

Identifiers

PMID37175449
PMCPMC10178507

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.