Evidence map›Paper›PMID 37175681›Full record

ArticleInternational journal of molecular sciences2023

The Toxicity of Protein Aggregates: New Insights into the Mechanisms.

Alessandra Bigi, Eva Lombardo, Roberta Cascella, Cristina Cecchi

Abstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandra BigiDepartment of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-1067-6288
Eva LombardoDepartment of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, 50134 Florence, Italy.
Roberta CascellaDepartment of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-9856-6843
Cristina CecchiDepartment of Experimental and Clinical Biomedical Sciences, Section of Biochemistry, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-8387-7737

Funding

Airalzh Foundation AGYR 2020, Project SENSITIZER to R.C.Regione Toscana FAS-Salute 2018, Project PRAMA to R.C. and C.C.University of Florence Fondi Ateneo to R.C. and C.C.
6 · The paper itself

Abstract

The aberrant aggregation of specific peptides and proteins is the common feature of a range of more than 50 human pathologies, collectively referred to as protein misfolding diseases [...].

Indexed as

Protein AggregatesProteostasis DeficienciesHumansPeptidesProtein FoldingProteinsPeptidesProtein AggregatesProteins

Identifiers

PMID37175681
PMCPMC10178715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.