Evidence map›Paper›PMID 37175764›Full record

ReviewInternational journal of molecular sciences2023

Impact of Gut Microbiota on the Peripheral Nervous System in Physiological, Regenerative and Pathological Conditions.

Sonia Calabrò, Svenja Kankowski, Matilde Cescon, Giovanna Gambarotta, Stefania Raimondo, Kirsten Haastert-Talini, Giulia Ronchi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  6. Review
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  11. Article
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  13. Review
  14. Article
  15. Gut microbiota regulates optic nerve fiber myelination.Frontiers in cell and developmental biology · 2025
    Article
  16. Article
  17. Progress on the mechanism of intestinal microbiota against colorectal cancer.Frontiers in cellular and infection microbiology · 2025
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sonia CalabròDepartment of Molecular Medicine, University of Padova, Via Ugo Bassi 58/B, 35131 Padova, Italy.ORCID 0009-0006-9146-1508
Svenja KankowskiHannover Medical School, Institute of Neuroanatomy and Cell Biology, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.ORCID 0000-0003-0387-3184
Matilde CesconDepartment of Molecular Medicine, University of Padova, Via Ugo Bassi 58/B, 35131 Padova, Italy.ORCID 0000-0001-7138-1857
Giovanna GambarottaDepartment of Clinical and Biological Sciences & Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Torino, Regione Gonzole 10, Orbassano, 10043 Torino, Italy.ORCID 0000-0002-8380-5925
Stefania RaimondoDepartment of Clinical and Biological Sciences & Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Torino, Regione Gonzole 10, Orbassano, 10043 Torino, Italy.ORCID 0000-0002-8907-473X
Kirsten Haastert-TaliniHannover Medical School, Institute of Neuroanatomy and Cell Biology, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.ORCID 0000-0003-2502-8969
Giulia RonchiDepartment of Clinical and Biological Sciences & Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Torino, Regione Gonzole 10, Orbassano, 10043 Torino, Italy.
Neuroscience Institute · ITMedizinische Hochschule Hannover · DEUniversity of Padua · IT

Funding

University of Torino Grant For Internationalization
6 · The paper itself

Abstract

It has been widely demonstrated that the gut microbiota is responsible for essential functions in human health and that its perturbation is implicated in the development and progression of a growing list of diseases. The number of studies evaluating how the gut microbiota interacts with and influences other organs and systems in the body and vice versa is constantly increasing and several 'gut-organ axes' have already been defined. Recently, the view on the link between the gut microbiota (GM) and the peripheral nervous system (PNS) has become broader by exceeding the fact that the PNS can serve as a systemic carrier of GM-derived metabolites and products to other organs. The PNS as the communication network between the central nervous system and the periphery of the body and internal organs can rather be affected itself by GM perturbation. In this review, we summarize the current knowledge about the impact of gut microbiota on the PNS, with regard to its somatic and autonomic divisions, in physiological, regenerative and pathological conditions.

Indexed as

Gastrointestinal MicrobiomeCentral Nervous SystemHumansPeripheral Nervous Systemgut microbiotanerve injury and regenerationperipheral nerveshort chain fatty acid

Identifiers

PMID37175764
PMCPMC10179357
OpenAlexW4367627570

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.