Evidence map›Paper›PMID 37176045›Full record

ArticleInternational journal of molecular sciences2023

Effective Pre-Clinical Treatment of Fish Envenoming with Polyclonal Antiserum.

Monica Lopes Ferreira, Maria Alice Pimentel Falcão, Fernanda Miriane Bruni, Vidal Haddad, Elineide Eugênio Marques, Carla Simone Seibert, Carla Lima

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Histopathological characterization of skin and muscle lesions induced by lionfish (The journal of venomous animals and toxins including tropical diseases · 2025
    Article
  2. A comprehensive overview of fish envenomation and venom toxicity in Brazil.The journal of venomous animals and toxins including tropical diseases · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Monica Lopes FerreiraImmunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
Maria Alice Pimentel FalcãoImmunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
Fernanda Miriane BruniImmunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.
Vidal HaddadFaculdade de Medicina, Universidade Estadual Paulista, Botucatu 18618-689, Brazil.
Elineide Eugênio MarquesEnvironmental Sciences, Campus of Palmas, Federal University of Tocantins, Palmas 77001-090, Brazil.
Carla Simone SeibertEnvironmental Sciences, Campus of Palmas, Federal University of Tocantins, Palmas 77001-090, Brazil.ORCID 0000-0002-3988-7767
Carla LimaImmunoregulation Unit of Laboratory of Applied Toxinology (CeTICs/FAPESP), Butantan Institute, São Paulo 05503-900, Brazil.ORCID 0000-0002-8161-966X
Instituto Butantan · BRUniversidade Federal do Tocantins · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

São Paulo Research Foundation 2005/58101-0São Paulo Research Foundation 2013/07467-1
6 · The paper itself

Abstract

Envenomation by venomous fish, although not always fatal, is capable of causing damage to homeostasis by activating the inflammatory process, with the formation of edema, excruciating pain, necrosis that is difficult to heal, as well as hemodynamic and cardiorespiratory changes. Despite the wide variety of pharmacological treatments used to manage acute symptoms, none are effective in controlling envenomation. Knowing the essential role of neutralizing polyclonal antibodies in the treatment of envenoming for other species, such as snakes, this work aimed to produce a polyclonal antiserum in mice and test its ability to neutralize the main toxic effects induced by the venoms of the main venomous Brazilian fish. We found that the antiserum recognizes the main toxins present in the different venoms of

Indexed as

BatrachoidiformesCatfishesFish VenomsPerciformesAnimalsImmune SeraMiceFish VenomsImmune SeraCathrops spixiifish venomneutralizing antibodypolyclonal antiserumPotamotrygon gr orbignyiScorpaena plumieriThalassophryne nattereritoxic effects

Identifiers

PMID37176045
PMCPMC10179662
OpenAlexW4375862733

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.