Evidence map›Paper›PMID 37176729›Full record

ReviewJournal of clinical medicine2023

The Pain Management of Trauma Patients in the Emergency Department.

Andrea Fabbri, Antonio Voza, Alessandro Riccardi, Sossio Serra, Fabio De Iaco, Study and Research Center of the Italian Society of Emergency Medicine (SIMEU)

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04705480 (Pregabalin vs. Gabapentin on Reducing Opioid Usage in Trauma Patients), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
27.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04705480 phase4completednot on this map

Pregabalin vs. Gabapentin on Reducing Opioid Usage in Trauma Patients

TypeinterventionalSponsorCAMC Health SystemRan2021 to 2024Enrolled109ConditionsAnalgesics, Gabapentin, Injuries, NarcoticsArmsPregabalin 50mg, Gabapentin 300mg, Neither Pregabalin nor Gabapentin
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Ketamine versus morphine for musculoskeletal trauma pain: a meta-analysis of randomized controlled trials.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Defining the need for analgesia in the emergency department: an international consensus statement.European journal of emergency medicine : official journal of the European Society for Emergency Medicine · 2026
    Article
  6. Article
  7. The assessment and management of acute trauma pain in a Cape Town, South Africa Emergency Centre: A retrospective chart review.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026
    Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Improving pain management for trauma patients at two Rwandan emergency departments.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Andrea FabbriEmergency Department, AUSL Romagna, Presidio Ospedaliero Morgagni-Pierantoni, 47121 Forlì, Italy.ORCID 0000-0002-9837-4638
Antonio VozaDepartment of Biomedical Sciences, IRCCS Humanitas Research Hospital, 20089 Milano, Italy.ORCID 0000-0001-7309-6929
Alessandro RiccardiUnit of Emergency Medicine, Ospedale San Paolo, 17121 Savona, Italy.ORCID 0000-0002-4936-1531
Sossio SerraEmergency Department, AUSL Romagna, Ospedale M. Bufalini, 47521 Cesena, Italy.
Fabio De IacoStruttura Complessa di Medicina di Emergenza Urgenza, Ospedale Maria Vittoria, ASL Città di Torino, 10144 Torino, Italy.
Study and Research Center of the Italian Society of Emergency Medicine (SIMEU)
IRCCS Humanitas Research Hospital · ITOspedale Maria Vittoria · ITOspedale “M. Bufalini” di Cesena · ITOspedale San Paolo · ITPresidio Ospedaliero · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vast majority of injured patients suffer from pain. Systematic assessment of pain on admission to the emergency department (ED) is a cornerstone of translating the best treatment strategies for patient care into practice. Pain must be measured with severity scales that are validated in clinical practice, including for specific populations (such as children and older adults). Although primary care ED of trauma patients focuses on resuscitation, diagnosis and treatment, pain assessment and management remains a critical element as professionals are not prepared to provide effective and early therapy. To date, most EDs have pain assessment and management protocols that take into account the patient's hemodynamic status and clinical condition and give preference to non-pharmacological approaches where possible. When selecting medications, the focus is on those that are least disruptive to hemodynamic status. Pain relief may still be necessary in hemodynamically unstable patients, but caution should be exercised, especially when using opioids, as absorption may be impaired or shock may be exacerbated. The analgesic dose of ketamine is certainly an attractive option. Fentanyl is clearly superior to other opioids in initial resuscitation and treatment as it has minimal effects on hemodynamic status and does not cause central nervous system depression. Inhaled analgesia techniques and ultrasound-guided nerve blocks are also increasingly effective solutions. A multimodal pain approach, which involves the use of two or more drugs with different mechanisms of action, plays an important role in the relief of trauma pain. All EDs must have policies and promote the adoption of procedures that use multimodal strategies for effective pain management in all injured patients.

Indexed as

analgesic doseemergency departmentmain drugsmultimodal approachpain relief

Identifiers

PMID37176729
PMCPMC10179230
OpenAlexW4372348090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.