Evidence map›Paper›PMID 37180735›Full record

ReviewJournal of bone oncology2023

Molecular and biologic biomarkers of Ewing sarcoma: A systematic review.

Mohammad Daher, Ziad Zalaquett, Ralph Chalhoub, Sami Abi Farraj, Majd Abdo, Amer Sebaaly, Hampig-Raphaël Kourie, Ismat Ghanem

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of bone oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mohammad DaherOrthopedic Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Ziad ZalaquettHematology-Oncology Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Ralph ChalhoubHematology-Oncology Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Sami Abi FarrajOrthopedic Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Majd AbdoHematology-Oncology Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Amer SebaalyOrthopedic Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Hampig-Raphaël KourieHematology-Oncology Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Ismat GhanemOrthopedic Department, Faculty of Medicine, Saint Joseph University of Beirut, Lebanon.
Saint Joseph University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With an annual incidence of less than 1%, Ewing sarcoma mainly occurs in children and young adults. It is not a frequent tumor but is the second most common bone malignancy in children. It has a 5-year survival rate of 65-75%; however, it has a poor prognosis when it relapses in patients. A genomic profile of this tumor can potentially help identify poor prognosis patients earlier and guide their treatment. A systematic review of the articles concerning genetic biomarkers in Ewing sarcoma was conducted using the Google Scholar, Cochrane, and PubMed database. There were 71 articles discovered. Numerous diagnostic, prognostic, and predictive biomarkers were found. However, more research is necessary to confirm the role of some of the mentioned biomarkers. .

Indexed as

BiologicBiomarkersBone tumorsEwing sarcomaGenesMolecular

Identifiers

PMID37180735
PMCPMC10173001
OpenAlexW4367057127

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.