Evidence map›Paper›PMID 37182921›Full record

ArticleSaudi medical journal2023

Clinical and pathological characteristics of extra-cranial germ cell tumors: A 30-year single-center experience in Saudi Arabia.

Dania A Monagel, Aletani Tala, Alghamdi Arwa, Banjar Sereen, Hakeem Ilana, Hannef Deena, Ahmed Omaima, Elimam Naglla

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Dania A MonagelFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Aletani TalaFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Alghamdi ArwaFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Banjar SereenFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Hakeem IlanaFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Hannef DeenaFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Ahmed OmaimaFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Elimam NagllaFrom the College of Medicine (Monagel, Tala, Arwa, Sereen, Ilana), King Saud bin Abdulaziz University for Health Sciences; from the Department of Medical Researches (Monagel), King Abdullah International Medical Research Center; from the Department of Oncology (Monagel, Omaima, Naglla), Ministry of the National Guard- Health Affairs; from the Center of Excellence in Genomic Medicine Research (Deena), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
King Abdullah International Medical Research Center · SANational Guard Health Affairs · SAKing Abdulaziz University · SAKing Saud bin Abdulaziz University for Health Sciences · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the clinical and pathological characteristics of extracranial germ cell tumors (GCTs) in children aged 0-168 months treated at the National Guard Hospital, Jeddah, Saudi Arabia from 1990 to 2020.

methodsIn this retrospective analysis, the data for all cases of GCTs were collected from 1990 to 2020. Statistical analyses were carried out using JMP software. The data was divided into 4 main categories: demographics, pathological/clinical features, recurrence, treatment and outcome.

resultsThe study included 50 patients, with a mean age at diagnosis of 56.52 months. The median follow-up duration was 30 months. Most tumors were in the gonads, and among the extragonadal tumors, the sacro-coccyx was the most frequent site of the disease.The most common histological subtype of GCTs is yolk sac tumor, accounting for 28% of cases. Of the 50 patients, 46% received chemotherapy, and 54% underwent surgery without chemotherapy. Ten (20%) patients experienced recurrence after treatment. At the last follow-up, 96% of the patients were alive, and only 2 of the patients died due to advanced disease.

conclusionOur findings were comparable to international data, but improvement in surveillance is required for long-term survivors.

Indexed as

Neoplasms, Germ Cell and EmbryonalChildChild, PreschoolHumansRetrospective StudiesSaudi Arabiachildhoodgerm cell tumorpediatric

Identifiers

PMID37182921
PMCPMC10187735
OpenAlexW4376642775

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.