ArticleCurrent oncology (Toronto, Ont.)2023
Clinicopathological Characteristics, Treatment Patterns, and Outcomes in Patients with Laryngeal Cancer.
Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Radiomics-based unsupervised clustering and deep learning nomogram for response prediction after neoadjuvant chemotherapy in locally advanced laryngeal cancer.BMC medical imaging · 2026Article
- A retrospective study of laryngeal squamous cell carcinoma and the significance of the PIK3CA mutation for survival.Molecular and clinical oncology · 2025Article
- [Integrated imaging and clinical features of glottic squamous cell carcinoma of the larynx: pathological association and prognosis assessment].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Article
- Analysis of the mortality trends of laryngeal cancer attributable to smoking worldwide from 1990 to 2021 and projections up to 2036.World journal of surgical oncology · 2025Article
- Development and validation of a multimodal feature fusion-based model for predicting postoperative recurrence-free survival in locally advanced laryngeal squamous cell carcinoma.Frontiers in oncology · 2025Article
- Identifying key pathogenic mechanisms and potential intervention targets for recurrence after laryngeal cancer treatment through bioinformatics screening.Translational cancer research · 2024Article
- lncRNA FLJ20021 regulates CDK1-mediated PANoptosis in a ZBP1-dependent manner to increase the sensitivity of laryngeal cancer-resistant cells to cisplatin.Discover oncology · 2024Article
- Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models.Scientific reports · 2023Article
Corrections and comments
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8 authors.
Funding
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Abstract
backgroundVarious factors can affect the survival of patients with laryngeal cancer (LC). In this retrospective study, we assessed clinicopathological features, their prognostic value, and treatment modalities for patients with confirmed squamous cell LC.
methodsWe collected patient data on demographics, clinicopathological characteristics, treatment patterns, and outcomes. The primary endpoints were overall survival (OS), disease-specific survival (DSS), disease-free survival (DFS), and locoregional control (LRC). We assessed survival using the Kaplan-Meier method and Cox regression model analyses of potential prognostic parameters.
resultsAfter a median follow-up of 76 months, 28 (33.3%) patients had a recurrence. The median OS was 78 months, with an event recorded in 50% of patients. The DSS median was not reached (NR) with a survival rate of 72.6%, the DFS survival rate was 66.7% with median NR, and the LRC survival rate was 72.6% with median NR. After conducting a multivariate analysis of significant variables, we found that only recurrence and lymphatic invasion had an independent effect on OS and recurrence in DSS, while subsite impacted DFS and LRC.
conclusionsSurvival trends were consistent with other studies, except for OS. Recurrence, lymphatic invasion, and subsite location were significant factors that impacted patient survival.
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