Evidence map›Paper›PMID 37186785›Full record

ArticleACS applied materials & interfaces2023

Osmotically Rupturing Phagosomes in Macrophages Using PNIPAM Microparticles.

Wenhao Cheng, Masahiro Fukuda, Sundol Kim, Yuan Liu, Xingchi Chen, Christina Holmes, Yan Li, Hoyong Chung, Yi Ren, Jingjiao Guan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Wenhao ChengDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Masahiro FukudaDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Sundol KimDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Yuan LiuDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Xingchi ChenDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Christina HolmesDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Yan LiDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Hoyong ChungDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.
Yi RenCollege of Medicine, Florida State University, Tallahassee, Florida 32306-4370, United States.
Jingjiao GuanDepartment of Chemical and Biomedical Engineering, FAMU-FSU College of Engineering, Florida State University, Tallahassee, Florida 32310-2870, United States.ORCID 0000-0002-8389-4067
Florida A&M University - Florida State University College of Engineering · USFlorida State University · US

Funding

Development of a Microdevice for Photoelectrical Stimulation of CellsR03EB028878 · NIBIB · FLORIDA STATE UNIVERSITY · PI GUAN, JINGJIAO · 2020 to 2021
$142k
Microdevice-Armed Macrophage For Treating CancerR03CA202334 · NCI · FLORIDA STATE UNIVERSITY · PI GUAN, JINGJIAO, REN, YI · 2017 to 2018
$141k
NCI NIH HHS R03 CA202334NIBIB NIH HHS R03 EB028878
6 · The paper itself

Abstract

The rupture of macrophage phagosomes has been implicated in various human diseases and plays a critical role in immunity. However, the mechanisms underlying this process are complex and not yet fully understood. This study describes the development of a robust engineering method for rupturing phagosomes based on a well-defined mechanism. The method utilizes microfabricated microparticles composed of uncrosslinked linear poly(

Indexed as

MacrophagesPhagosomesAcrylic ResinsHumansAcrylic Resinspoly-N-isopropylacrylamidemacrophageosmotic pressurephagosomePNIPAMrupture

Identifiers

PMID37186785
PMCPMC10426762
OpenAlexW4376604490

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.