Evidence map›Paper›PMID 37188469›Full record

ArticleBMJ open2023

Implementation of a culturally competent

Justin D Smith, Akansha Agrawal, Catherine Wicklund, Debra Duquette, John Friedewald, Luke V Rasmussen, Jessica Gacki-Smith, S Darius Tandon, Lutfiyya N Muhammad, Clyde W Yancy and 5 more

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04910867 naactive not recruitingnot on this map

Integrating a Culturally Competent APOL1 Genetic Testing Program Into Living Donor Evaluation

TypeinterventionalSponsorNorthwestern UniversityRan2021 to 2026Enrolled206ConditionsChronic Kidney Diseases, Apolipoprotein L1, Kidney TransplantationArmsComponents of Genetic Counseling, APOL1 genetic testing, EHR integration
NCT04999436 nacompletednot on this map

APOL1 Genetic Testing Program for Living Donors, Part 2

TypeinterventionalSponsorNorthwestern UniversityRan2022 to 2025Enrolled35ConditionsChronic Kidney Diseases, Genetic PredispositionArmsAPOL1 Counseling Training Program
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Kidney medicine · 2025
    Review
  5. Contextual factors of implementing APOL1 genetic testing into living kidney donor clinical evaluation.Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Article
  6. Advancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Justin D SmithDepartment of Population Health Sciences, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-3264-8082
Akansha AgrawalMedicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-2662-7023
Catherine WicklundObstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0001-5725-2872
Debra DuquetteMedicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-4664-0495
John FriedewaldMedicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-9344-9928
Luke V RasmussenDivision of Health and Biomedical Informatics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Jessica Gacki-SmithCenter for Health Services and Outcomes Research, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-7000-9014
S Darius TandonMedical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Lutfiyya N MuhammadDepartment of Preventive Medicine-Division of Biostatistics, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-8655-1484
Clyde W YancyDepartment of Medicine-Division of Cardiology, Northwestern University, Evanston, Illinois, USA.
Siyuan DongDepartment of Preventive Medicine-Division of Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Matthew CooperSurgery, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0002-3438-9638
Alexander GilbertMedicine, Georgetown University Medical Center, Washington, District of Columbia, USA.
Aneesha ShettyMedicine, The University of Arizona College of Medicine Tucson, Tucson, Arizona, USA.
Elisa J GordonSurgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA elisa.gordon@vumc.org.ORCID 0000-0003-0969-1998
Northwestern University · USGeorgetown University · USMedical College of Wisconsin · USUniversity of Arizona · USVanderbilt University Medical Center · US

Funding

Integrating a culturally competent APOL1 genetic testing program into living donor evaluationR01DK128207 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AGRAWAL, AKANSHA, FRIEDEWALD, JOHN J · 2021 to 2025
$3.3M
NIDDK NIH HHS R01 DK128207
6 · The paper itself

Abstract

introductionWhile living donor (LD) kidney transplantation is the optimal treatment for patients with kidney failure, LDs assume a higher risk of future kidney failure themselves. LDs of African ancestry have an even greater risk of kidney failure post-donation than White LDs. Because evidence suggests that Apolipoprotein L1 ( METHODS AND ANALYSIS: Using a non-randomised, pre-post trial design in two transplant centres (Chicago, IL, and Washington, DC), we will evaluate the effectiveness of culturally competent ETHICS AND DISSEMINATION: This study will create a model for

trial registrationClinicalTrials.gov Identifier: NCT04910867. Registered 8 May 2021, https://register. CLINICALTRIALS: gov/prs/app/action/SelectProtocol?sid=S000AWZ6&selectaction=Edit&uid=U0001PPF&ts=7&cx=-8jv7m2 ClinicalTrials.gov Identifier: NCT04999436. Registered 5 November 2021, https://register. CLINICALTRIALS: gov/prs/app/action/SelectProtocol?sid=S000AYWW&selectaction=Edit&uid=U0001PPF&ts=11&cx=9tny7v.

Indexed as

Black or African AmericanKidney TransplantationLiving DonorsRenal InsufficiencyApolipoprotein L1Cultural CompetencyGenetic TestingHumansAPOL1 protein, humanApolipoprotein L1End stage renal failureETHICS (see Medical Ethics)GENETICSOrganisation of health servicesQUALITATIVE RESEARCHRenal transplantation

Identifiers

PMID37188469
PMCPMC10186444
OpenAlexW4376610357

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.