Evidence map›Paper›PMID 37189407›Full record

ArticleBiomolecules2023

Regulation of Cx43 Gap Junction Intercellular Communication by Bruton's Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase.

Ishika Basu, Hanjun Li, Andrew J Trease, Paul L Sorgen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ishika BasuDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Hanjun LiDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Andrew J TreaseDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Paul L SorgenDepartment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
University of Nebraska Medical Center · US

Funding

Mechanisms of Gap Junction RegulationR01GM072631 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SORGEN, PAUL L · 2006 to 2025
$6.4M
Research Pilot Project ProgramP30GM106397 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WAHL, JAMES K · 2013 to 2017
$4.9M
LSM 710 Zeiss Confocal MicroscopeS10RR027301 · NCRR · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CHRISTMAN, JUDITH K · 2010 to 2010
$461k
NCRR NIH HHS S10 RR027301NIGMS NIH HHS P30 GM106397NIGMS NIH HHS R01 GM072631NIH HHS GM072631NIH HHS P30GM106397NIH HHS S10RR027301
6 · The paper itself

Abstract

T and B cell receptor signaling involves the activation of Akt, MAPKs, and PKC as well as an increase in intracellular Ca

Indexed as

Connexin 43Interleukin-2Agammaglobulinaemia Tyrosine KinaseCell CommunicationFocal Adhesion Kinase 2Gap JunctionsHumansPhosphorylationReceptors, Antigen, B-CellT-LymphocytesTyrosineAgammaglobulinaemia Tyrosine KinaseConnexin 43Focal Adhesion Kinase 2Interleukin-2Receptors, Antigen, B-CellTyrosineBTKCx43gap junctionsITKphosphorylation

Identifiers

PMID37189407
PMCPMC10135648
OpenAlexW4363647903

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.