Evidence map›Paper›PMID 37191063›Full record

ReviewThe British journal of radiology2023

Neurofluids and the glymphatic system: anatomy, physiology, and imaging.

Danny Jj Wang, Jun Hua, Di Cao, Mai-Lan Ho

Open access · hybridAbstract readReview
In one paragraph

Review in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Ocular Solute Movement Direction and Intracranial Clearance via Vitreous Gadolinium-based Contrast Agent MR Imaging: Potential as a Novel Biomarker for Glymphatic Dysfunction.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. PET Imaging of Neurofluids.Neuroimaging clinics of North America · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. The Glymphatic System and Its Role in Neurovascular Diseases.Journal of neuroendovascular therapy · 2025
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Danny Jj WangMark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, United States.
Jun HuaThe Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Di CaoThe Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Mai-Lan HoNationwide Children's Hospital and The Ohio State University, Columbus, Ohio, United States.ORCID 0000-0002-9455-1350
Kennedy Krieger Institute · USNationwide Children's Hospital · USUniversity of Southern California · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Stewart H Mostofsky · 2020 to 2026
$9.9M
NICHD NIH HHS P50 HD103538
6 · The paper itself

Abstract

First described in 2012, the glymphatic system is responsible for maintaining homeostasis within the central nervous system, including nutrient delivery, waste clearance, and consistency of the ionic microenvironment. It is comprised of glial cells and barrier systems that modulate neurofluid production, circulation, and exchange. Experimental interrogation of neurofluid dynamics is restricted to

Indexed as

Glymphatic SystemNervous System DiseasesAnimalsBrainCentral Nervous SystemDiagnostic ImagingHumans

Identifiers

PMID37191063
PMCPMC10607419
OpenAlexW4376642549

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.