Evidence map›Paper›PMID 37193203›Full record

ArticleDiabetes spectrum : a publication of the American Diabetes Association2023

Practical Aspects and Exercise Safety Benefits of Automated Insulin Delivery Systems in Type 1 Diabetes.

Dessi P Zaharieva, Dale Morrison, Barbora Paldus, Rayhan A Lal, Bruce A Buckingham, David N O'Neal

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Diabetes spectrum : a publication of the American Diabetes Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06082973 (Evaluation of Dual-hormone Artificial Pancreas With Closed-loop Glucose Control Versus Single-hormone With Carbohydrate Recommendations Under Unannounced Exercise and Meal Challenge in Adults With Type 1 Diabetes.), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06082973 nacompletednot on this mapstarted 2024, after this paper: background citation

Evaluation of Dual-hormone Artificial Pancreas With Closed-loop Glucose Control Versus Single-hormone With Carbohydrate Recommendations Under Unannounced Exercise and Meal Challenge in Adults With Type 1 Diabetes.

TypeinterventionalSponsorUniversitat Politècnica de ValènciaRan2024 to 2025Enrolled15ConditionsType 1 DiabetesArmsAutomated insulin delivery system algorithm with a dual-hormone configuration (insulin and glucagon) for glucose control, Automated insulin delivery system with a single-hormone configuration (insulin) with rescue carbohydrate recommendations for glucose control
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Observational
  7. Article
  8. Managing obesity in adults with type 1 diabetes.Diabetes research and clinical practice · 2025
    Review
  9. Review
  10. Review
  11. Automated Insulin Delivery for Type 1 Diabetes: Present and Future.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. The Hybrid Closed-Loop System Tandem t:slim X2™ with Control-IQ Technology: Expert Recommendations for Better Management and Optimization.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
  16. Review
  17. Article
  18. Physical Activity Management for Youth With Type 1 Diabetes: Supporting Active and Inactive Children.Diabetes spectrum : a publication of the American Diabetes Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dessi P ZaharievaDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID https://orcid.org/0000-0002-9374-8469
Dale MorrisonDepartment of Medicine, The University of Melbourne, Melbourne, Australia.ORCID https://orcid.org/0000-0001-6269-4923
Barbora PaldusDepartment of Medicine, The University of Melbourne, Melbourne, Australia.ORCID https://orcid.org/0000-0002-4303-0125
Rayhan A LalDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID https://orcid.org/0000-0002-8055-944X
Bruce A BuckinghamDivision of Endocrinology, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.
David N O'NealDepartment of Medicine, The University of Melbourne, Melbourne, Australia.ORCID https://orcid.org/0000-0002-0870-4032
Stanford University · USThe University of Melbourne · AU

Funding

Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
The Optimal Pathway to Implanted Autonomous Insulin DeliveryK23DK122017 · NIDDK · STANFORD UNIVERSITY · PI LAL, RAYHAN · 2020 to 2024
$958k
NIDDK NIH HHS K23 DK122017NIDDK NIH HHS P30 DK116074
6 · The paper itself

Abstract

Regular exercise is essential to overall cardiovascular health and well-being in people with type 1 diabetes, but exercise can also lead to increased glycemic disturbances. Automated insulin delivery (AID) technology has been shown to modestly improve glycemic time in range (TIR) in adults with type 1 diabetes and significantly improve TIR in youth with type 1 diabetes. Available AID systems still require some user-initiated changes to the settings and, in some cases, significant pre-planning for exercise. Many exercise recommendations for type 1 diabetes were developed initially for people using multiple daily insulin injections or insulin pump therapy. This article highlights recommendations and practical strategies for using AID around exercise in type 1 diabetes.

Identifiers

PMID37193203
PMCPMC10182962
OpenAlexW4376604605

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.