Evidence map›Paper›PMID 37196080›Full record

ReviewScience advances2023

Breakthrough treatments for accelerated wound healing.

Benjamin R Freedman, Charles Hwang, Simon Talbot, Brian Hibler, Simon Matoori, David J Mooney

Abstract readReview
In one paragraph

Review in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
172citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

172 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Fish Collagen Hydrolysates in Wound Healing: A Patent Review.ACS pharmacology & translational science · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

112 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Benjamin R FreedmanJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.ORCID 0000-0001-9406-773X
Charles HwangDivision of Plastic Surgery, Brigham and Women's Hospital, Harvard University, Boston, MA, USA.ORCID 0000-0002-3897-6813
Simon TalbotDivision of Plastic Surgery, Brigham and Women's Hospital, Harvard University, Boston, MA, USA.ORCID 0000-0002-6092-7401
Brian HiblerSchweiger Dermatology Group, New York, NY, USA.ORCID 0000-0001-6497-8954
Simon MatooriJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.ORCID 0000-0002-1559-0950
David J MooneyJohn A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.ORCID 0000-0001-6299-1194

Funding

Supplement Multifunctional Tough Adhesive Hydrogels to Recruit, Expand, and Deliver Tendon Cells During Aging and InjuryR00AG065495 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Benjamin Ross Freedman · 2023 to 2026
$842k
Multifunctional tough adhesive hydrogels to recruit, expand, and deliver tendoncells during aging and injuryK99AG065495 · NIA · HARVARD UNIVERSITY · PI FREEDMAN, BENJAMIN ROSS · 2020 to 2022
$341k
NIA NIH HHS K99 AG065495NIA NIH HHS R00 AG065495
6 · The paper itself

Abstract

Skin injuries across the body continue to disrupt everyday life for millions of patients and result in prolonged hospital stays, infection, and death. Advances in wound healing devices have improved clinical practice but have mainly focused on treating macroscale healing versus underlying microscale pathophysiology. Consensus is lacking on optimal treatment strategies using a spectrum of wound healing products, which has motivated the design of new therapies. We summarize advances in the development of novel drug, biologic products, and biomaterial therapies for wound healing for marketed therapies and those in clinical trials. We also share perspectives for successful and accelerated translation of novel integrated therapies for wound healing.

Indexed as

Biocompatible MaterialsWound HealingHumansBiocompatible Materials

Identifiers

PMID37196080
PMCPMC10191440

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.