Evidence map›Paper›PMID 37198101›Full record

ArticleBritish journal of pharmacology2023

BQ788 reveals glial ET

Elvio Mazzotta, Iveta Grants, Egina Villalobos-Hernandez, Samhita Chaudhuri, Jonathon L McClain, Luisa Seguella, Derek M Kendig, Bryan A Blakeney, Srinivasa K Murthy, Reiner Schneider and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. EDNRB2 regulates fate, migration, and maturation of hair cell precursors in regenerating avian auditory epithelium explants.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. The Physiology of Enteric Glia.Annual review of physiology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Elvio MazzottaDepartment of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
Iveta GrantsDepartment of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
Egina Villalobos-HernandezDepartment of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
Samhita ChaudhuriDepartment of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
Jonathon L McClainDepartment of Physiology, Michigan State University, East Lansing, Michigan, USA.
Luisa SeguellaDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
Derek M KendigDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA.
Bryan A BlakeneyDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA.
Srinivasa K MurthyDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA.
Reiner SchneiderDepartment of Surgery, University of Bonn, Bonn, Germany.
Patrick LevenDepartment of Surgery, University of Bonn, Bonn, Germany.
Sven WehnerDepartment of Surgery, University of Bonn, Bonn, Germany.
Alan HarzmanDepartment of GI Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
John R GriderDepartment of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA.
Brian D GulbransenDepartment of Physiology, Michigan State University, East Lansing, Michigan, USA.
Fedias L ChristofiDepartment of Anesthesiology, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0003-2773-6846
The Ohio State University Wexner Medical Center · USVirginia Commonwealth University · USUniversity of Bonn · DEMichigan State University · USSapienza University of Rome · IT

Funding

HORMONAL INTEGRATION OF EXOCRINE AND ENDOCRINE ORGANSR01DK015564 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI KARNAM, S MURTHY · 1986 to 2020
$6.7M
ROLE OF GUT PEPTIDES IN INTESTINAL PERISTALSISR01DK034153 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI GRIDER, JOHN R · 1987 to 2019
$5.5M
FUNCTION OF GUT PEPTIDES ISOLATED GUT MUSCLE CELLSR01DK028300 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI KARNAM, S MURTHY · 1986 to 2017
$5.2M
Role of enteric glia in the death of neurons during gut inflammationR01DK103723 · NIDDK · MICHIGAN STATE UNIVERSITY · PI BRIAN D. GULBRANSEN · 2015 to 2026
$4.7M
Enteric glia and visceral painR01DK120862 · NIDDK · MICHIGAN STATE UNIVERSITY · PI BRIAN D. GULBRANSEN · 2019 to 2026
$3.0M
Enteric glial ETBR signaling in postoperative ileusR01DK125809 · NIDDK · OHIO STATE UNIVERSITY · PI CHRISTOFI, FEDIAS LEONTIOU · 2020 to 2023
$1.6M
Human enteric glia: A novel target for motility and postoperative ileusR01DK113943 · NIDDK · OHIO STATE UNIVERSITY · PI CHRISTOFI, FEDIAS LEONTIOU, GRIDER, JOHN R · 2017 to 2019
$1.4M
NIDDK NIH HHS R01 DK015564NIDDK NIH HHS R01 DK028300NIDDK NIH HHS R01 DK034153NIDDK NIH HHS R01 DK103723NIDDK NIH HHS R01 DK113943NIDDK NIH HHS R01 DK120862NIDDK NIH HHS R01 DK125809
6 · The paper itself

Abstract

background and purposeET-1 signalling modulates intestinal motility and inflammation, but the role of ET-1/ET EXPERIMENTAL APPROACH: We studied ET KEY

resultsIn the muscularis externa ET CONCLUSION AND IMPLICATIONS: Enteric glial ET-1/ET

Indexed as

GliotoxinIleusAnimalsCholinergic AgentsGastrointestinal MotilityInflammationMiceNeurogliaNeuronsOligopeptidesPiperidinesBQ 788Cholinergic AgentsGliotoxinOligopeptidesPiperidinesenteric gliaET-1ETB receptorinflammationintestinal motilitypost-operative ileus

Identifiers

PMID37198101
PMCPMC11085045
OpenAlexW4376866402

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.