ArticleCirculation2023
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Article in Circulation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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0cells of the map it votes in
50citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 54 citations in OpenAlex.
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Corrections and comments
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Authors and funding
27 authors at 11 institutions in 6 countries.
Wei Zhang *Vascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0002-2077-3188
Jinjing Zhao *Department of Molecular and Cellular Physiology, Albany Medical College, NY (J.Z., W.W., Y.W.L., P.G., M.C., M.M.B., X.L.).
Lin DengCentre for Cardiovascular Science, University of Edinburgh, Scotland (L.D., M.D.B., M.B., J.R., A.H.B.).
Nestor IshimweVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0001-6379-4109
Jessica PauliDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Germany (J.P., W.K., L.M.).ORCID 0000-0001-5984-3529
Wen WuDepartment of Molecular and Cellular Physiology, Albany Medical College, NY (J.Z., W.W., Y.W.L., P.G., M.C., M.M.B., X.L.).
Shengshuai ShanVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0003-1152-6609
Wolfgang KempfDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Germany (J.P., W.K., L.M.).
Margaret D BallantyneCentre for Cardiovascular Science, University of Edinburgh, Scotland (L.D., M.D.B., M.B., J.R., A.H.B.).
David KimVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0001-6896-6950
Qing LyuVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).
Matthew BennettCentre for Cardiovascular Science, University of Edinburgh, Scotland (L.D., M.D.B., M.B., J.R., A.H.B.).ORCID 0000-0001-9819-3397
Julie RodorCentre for Cardiovascular Science, University of Edinburgh, Scotland (L.D., M.D.B., M.B., J.R., A.H.B.).ORCID 0000-0003-2900-5780
Adam W TurnerCenter for Public Health Genomics (A.W.T., C.L.M.), University of Virginia, Charlottesville.
Yao Wei LuDepartment of Molecular and Cellular Physiology, Albany Medical College, NY (J.Z., W.W., Y.W.L., P.G., M.C., M.M.B., X.L.).ORCID 0000-0001-6200-2974
Ping GaoDepartment of Molecular and Cellular Physiology, Albany Medical College, NY (J.Z., W.W., Y.W.L., P.G., M.C., M.M.B., X.L.).
Mihyun ChoiDepartment of Molecular and Cellular Physiology, Albany Medical College, NY (J.Z., W.W., Y.W.L., P.G., M.C., M.M.B., X.L.).ORCID 0000-0002-3085-7342
Ganesh WarthiVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).
Ha Won KimVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0001-6272-4248
Margarida M BarrosoDepartment of Molecular and Cellular Physiology, Albany Medical College, NY (J.Z., W.W., Y.W.L., P.G., M.C., M.M.B., X.L.).ORCID 0000-0002-0407-3181
William B BryantVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).
Clint L MillerCenter for Public Health Genomics (A.W.T., C.L.M.), University of Virginia, Charlottesville.ORCID 0000-0003-4276-3607
Neal L WeintraubVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0002-5138-3705
Lars MaegdefesselDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Germany (J.P., W.K., L.M.).ORCID 0000-0001-5228-2634
Joseph M MianoVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0001-7522-3207
Andrew H BakerCentre for Cardiovascular Science, University of Edinburgh, Scotland (L.D., M.D.B., M.B., J.R., A.H.B.).ORCID 0000-0003-1441-5576
Xiaochun LongVascular Biology Center, Medical College of Georgia at Augusta University (W.Z., N.I., S.S., D.K., Q.L., G.W., H.W.K., W.B.B., N.L.W., J.M.M., X.L.).ORCID 0000-0001-9714-0023
Albany Medical Center Hospital · USAugusta University · USSarojini Naidu Medical College · INTUM Klinikum · DEUniversity of Edinburgh · GBHsin Sheng College of Medical Care and Management · TWJohnson & Johnson (United Kingdom) · GBQueen Margaret University · GBSt. Joseph Hospital · USUniversity of Virginia · USVirginia Department of Health · US
Funding
Multimodal genetic regulatory architecture of coronary artery diseaseR01HL148239 · NHLBI · UNIVERSITY OF VIRGINIA · PI Clint L Miller · 2019 to 2026
$4.2MNovel Role of MAPK14 in Regulation of VSMC Contractile PhenotypeR01HL122686 · NHLBI · AUGUSTA UNIVERSITY · PI LONG, XIAOCHUN · 2014 to 2022
$4.0MIn vivo Macroscopic Fluorescence Lifetime Molecular Optical ImagingR01CA250636 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2020 to 2023
$2.9MNeuronal HDAC9, Synaptic Plasticity and Alzheimer's DiseaseR01AG076235 · NIA · AUGUSTA UNIVERSITY · PI Xin-Yun Lu, Neal L Weintraub · 2022 to 2026
$2.8MFunction and Regulation of TSPAN2 in Vascular DiseaseR01HL139794 · NHLBI · AUGUSTA UNIVERSITY · PI LONG, XIAOCHUN · 2019 to 2023
$2.7MFunctional genomics investigation of pleiotropic vascular disease lociR01HL164577 · NHLBI · UNIVERSITY OF VIRGINIA · PI MILLER, CLINT L · 2022 to 2025
$2.3MTranscriptional Control of Myocardin and the MYOCARDomeR01HL138987 · NHLBI · UNIVERSITY OF ROCHESTER · PI MIANO, JOSEPH M · 2018 to 2021
$2.3MRegulation and Function of SRF in Vascular PathiobiologyR01HL147476 · NHLBI · UNIVERSITY OF ROCHESTER · PI MIANO, JOSEPH M · 2019 to 2022
$2.1MMechanisms of myeloperoxidase and Nox4 interactions in abdominal aortic aneurysmR01HL142097 · NHLBI · AUGUSTA UNIVERSITY · PI WEINTRAUB, NEAL L · 2018 to 2021
$2.1MBritish Heart Foundation FS/18/10/33413British Heart Foundation RG/20/5/34796NCI NIH HHS R01 CA250636NHLBI NIH HHS R01 HL122686NHLBI NIH HHS R01 HL138987NHLBI NIH HHS R01 HL139794NHLBI NIH HHS R01 HL142097NHLBI NIH HHS R01 HL147476NHLBI NIH HHS R01 HL148239NHLBI NIH HHS R01 HL164577NIA NIH HHS R01 AG076235
Abstract
backgroundActivation of vascular smooth muscle cell (VSMC) inflammation is vital to initiate vascular disease. The role of human-specific long noncoding RNAs in VSMC inflammation is poorly understood.
methodsBulk RNA sequencing in differentiated human VSMCs revealed a novel human-specific long noncoding RNA called inflammatory MKL1 (megakaryoblastic leukemia 1) interacting long noncoding RNA (
results
conclusionsThese findings elucidate an important pathway of VSMC inflammation involving an
Indexed as
Aortic Aneurysm, AbdominalRNA, Long NoncodingAnimalsCell ProliferationCells, CulturedHumansInflammationLuciferasesMiceMice, TransgenicMuscle, Smooth, VascularMyocytes, Smooth MuscleNF-kappa BTrans-ActivatorsUbiquitin ThiolesteraseLuciferasesMRTFA protein, humanNF-kappa BRNA, Long NoncodingTrans-ActivatorsUbiquitin ThiolesteraseUSP10 protein, humaninflammationmice, transgenicmyocytes, smooth muscleRNA, long noncodingubiquitination
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.