Evidence map›Paper›PMID 37200814›Full record

ArticleACS pharmacology & translational science2023

Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products.

Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan and 7 more

Open access · greenAbstract read
In one paragraph

Article in ACS pharmacology & translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Adam YasgarNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.ORCID https://orcid.org/0000-0001-7350-1402
Danielle BougieNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Richard T EastmanNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.ORCID https://orcid.org/0000-0003-3580-380X
Ruili HuangNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Misha ItkinNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Jennifer KouznetsovaNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Caitlin LynchNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Crystal McKnightNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Mitch MillerNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Deborah K NganNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Tyler PeryeaNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Pranav ShahNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Paul ShinnNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Menghang XiaNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.ORCID https://orcid.org/0000-0001-7285-8469
Xin XuNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Alexey V ZakharovNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.ORCID https://orcid.org/0000-0003-2466-1711
Anton SimeonovNational Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
National Institutes of Health · US

Funding

Research Services Section (RSS)ZICTR000242 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI WILSON, KELLI · 2015 to 2025
$64.9M
Toxicology in the 21st Century Program (Tox21) - Systems ToxicologyZIATR000038 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI XIA, MENGHANG · 2015 to 2025
$5.7M
Toxicology in the 21st Century Program (Tox21) - Computational ToxicologyZIATR000040 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI HUANG, RUILI · 2016 to 2025
$3.5M
Project 2 - Effects of Herb Fractions on Cell Function/Regulation:U19CA128534 · NCI · HARVARD MEDICAL SCHOOL · PI HAHN, ROBERT A · 2006 to 2009
$1.8M
NCI NIH HHS U19 CA128534
6 · The paper itself

Abstract

Dietary supplements and natural products are often marketed as safe and effective alternatives to conventional drugs, but their safety and efficacy are not well regulated. To address the lack of scientific data in these areas, we assembled a collection of Dietary Supplements and Natural Products (DSNP), as well as Traditional Chinese Medicinal (TCM) plant extracts. These collections were then profiled in a series of

Identifiers

PMID37200814
PMCPMC10186358
OpenAlexW4365509510

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.