ReviewNature aging2023
Social participation and risk of developing dementia.
Review in Nature aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
106 citing papers in PubMed, 1 synthesis or guideline pooled it, 176 citations in OpenAlex.
- Shared reading interventions to promote psychosocial well-being in older adults: a systematic review.Health promotion international · 2025Pooled it
- Quality over quantity - rethinking social participation in dementia prevention: results from the AgeWell.de trial.Social psychiatry and psychiatric epidemiology · 2026Trial
- Trial
- Associations of Social Engagement and Perceived Interpersonal Connectedness With Cognitive, Mental, and Physical Health in American Indian and Alaska Native Adults.Journal of aging and health · 2026Article
- Social engagement, formal education, and cognitive outcomes among older adults in India: A longitudinal population-based study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Arthritis and longitudinal trajectories of depressive symptoms and cognition in middle-aged and older adults: a prospective tri-cohort study.Archives of public health = Archives belges de sante publique · 2026Article
- A Moderated Mediation Model Linking Speech-in-Noise Exposure, Speech Perception in Noise Ability, Loneliness, and Depression.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Changes in social participation between ages 65 and 70 and incident dementia: a Bayesian competing risk analysis.BMC geriatrics · 2026Article
- The social environment and cognitive aging over the life course: laying out critical concepts and research gaps.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Social frailty and mortality risk in middle-aged and older adults: a prospective cohort study.GeroScience · 2026Article
- Association between intrinsic capacity and dementia risk in older Mexicans.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- High-Impact Participation? Social Activities, Activity Frequency, and Older Adult Cognition.Journal of aging and health · 2026Article
- Accelerated biological aging and brain structural alterations linking air pollution to dementia risk: a prospective cohort study.The journal of nutrition, health & aging · 2026Article
- Integrating noise as a risk factor in studies of Alzheimer's disease and dementia: Guidance for epidemiologic research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- AI-Enhanced Automatic Life Story Structuring for Reminiscence Therapy in Older Adults: Technical Feasibility Study.JMIR aging · 2026Article
- Association Between Social Participation, Physical Activity, and Intrinsic Capacity Decline: Empirical Evidence from the CHARLS.Healthcare (Basel, Switzerland) · 2026Article
- Psychometric Properties of the Italian Adaptation of the Subjective Cognitive Reserve Questionnaire Based on Modifiable Lifestyle Factors (SCR-Q).Healthcare (Basel, Switzerland) · 2026Article
- Socioeconomic status modifies the association between adherence to the Mediterranean diet and cognitive outcomes: results from the Collaborative PROMED-COG Pooled Cohorts Study.Social psychiatry and psychiatric epidemiology · 2026Article
- Social determinants of health, behavioral factors, and incident dementia: a prospective cohort study.Alzheimer's research & therapy · 2026Article
- The interplay of life satisfaction and cognitive reserve: implications for cognitive changes in old age.BMC geriatrics · 2026Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 7 institutions in 8 countries.
Funding
Abstract
The increasing number of people with dementia globally illustrates the urgent need to reduce dementia's scale and impact. Lifetime social participation may affect dementia risk by increasing cognitive reserve, and through brain maintenance by reducing stress and improving cerebrovascular health. It may therefore have important implications for individual behavior and public health policy aimed at reducing dementia burden. Observational study evidence indicates that greater social participation in midlife and late life is associated with 30-50% lower subsequent dementia risk, although some of this may not be causal. Social participation interventions have led to improved cognition but, partly due to short follow-up and small numbers of participants, no reduction in risk of dementia. We summarize the evidence linking social participation with dementia, discuss potential mechanisms by which social participation is likely to reduce and mitigate the impact of neuropathology in the brain, and consider the implications for future clinical and policy dementia prevention interventions.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.