SynthesisSports medicine - open2023
Best Time of Day for Strength and Endurance Training to Improve Health and Performance? A Systematic Review with Meta-analysis.
Synthesis in Sports medicine - open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601660 (Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical guidelines on physical activity and exercise therapy for Chinese adults with type 2 diabetes: A clinical practice guideline from the Chinese Society of Endocrinology.Journal of sport and health science · 2026Guideline
- Effect of circadian rhythm and menstrual cycle on physical performance in women: a systematic review.Frontiers in physiology · 2024Pooled it
- Effects of Acute Caffeine Ingestion on Morning Strength, Power and Repeated Sprint Measures in Males: A Standardized Approach.Nutrients · 2026Trial
- Effects of Caffeine Ingestion on Morning Cognitive and Muscle Strength Measures in Males: A Standardized Approach.Nutrients · 2026Trial
- Unlocking the potential of circadian biology for cardiovascular health.Physiological reviews · 2026Review
- Exercise Timing in Sport: Molecular and Physiological Mechanisms Linking Performance, Recovery, and Biological Cost.International journal of molecular sciences · 2026Review
- Reallocating morning physical activity to later-day activity and its association with type 2 diabetes incidence: The Maastricht Study.Diabetes, obesity & metabolism · 2026Article
- Impacts of exercise, renin-angiotensin system modulation or both on skeletal muscle circadian gene expression.Experimental physiology · 2026Article
- Exercise benefits in metabolism on cardiovascular disease.Frontiers in cardiovascular medicine · 2026Review
- Effects of preferred music listening on physical and psychological parameters in sports: a systematic review and meta-analysis with meta-regression.BMC sports science, medicine & rehabilitation · 2025Article
- Beyond FITT: addressing density in understanding the dose-response relationships of physical activity with health-an example based on brain health.European journal of applied physiology · 2025Review
- Development and Implementation of a Core Training Protocol: Effects on Muscle Activation, Hypertrophy, Balance, and Quality of Life in Recreationally Active Adults.Methods and protocols · 2025Article
- Muscle Rev-erb controls time-dependent adaptations to chronic exercise in mice.Nature communications · 2025Article
- Article
- Associations between the timing of 24 h physical activity and diabetes mellitus: results from a nationally representative sample of the US population.Diabetologia · 2025Article
- Comparative effectiveness of morning and evening aerobic exercise on weight loss and physical fitness in Chinese college students with overweight and obesity.BMC sports science, medicine & rehabilitation · 2025Article
- Circadian Regulation for Optimizing Sport and Exercise Performance.Clocks & sleep · 2025Review
- Timing of resistance exercise and cardiometabolic outcomes in adults with prediabetes: a secondary analysis.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- International Ski and Snowboard Federation (FIS) consensus statement on training and testing in competitive alpine and freestyle skiers and snowboarders.BMJ open sport & exercise medicine · 2025Article
- Alterations in Circadian Rhythms, Sleep, and Physical Activity in COVID-19: Mechanisms, Interventions, and Lessons for the Future.Molecular neurobiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundCurrent recommendations for physical exercise include information about the frequency, intensity, type, and duration of exercise. However, to date, there are no recommendations on what time of day one should exercise. The aim was to perform a systematic review with meta-analysis to investigate if the time of day of exercise training in intervention studies influences the degree of improvements in physical performance or health-related outcomes.
methodsThe databases EMBASE, PubMed, Cochrane Library, and SPORTDiscus were searched from inception to January 2023. Eligibility criteria were that the studies conducted structured endurance and/or strength training with a minimum of two exercise sessions per week for at least 2 weeks and compared exercise training between at least two different times of the day using a randomized crossover or parallel group design.
resultsFrom 14,125 screened articles, 26 articles were included in the systematic review of which seven were also included in the meta-analyses. Both the qualitative synthesis and the quantitative synthesis (i.e., meta-analysis) provide little evidence for or against the hypothesis that training at a specific time of day leads to more improvements in performance-related or health-related outcomes compared to other times. There was some evidence that there is a benefit when training and testing occur at the same time of day, mainly for performance-related outcomes. Overall, the risk of bias in most studies was high.
conclusionsThe current state of research provides evidence neither for nor against a specific time of the day being more beneficial, but provides evidence for larger effects when there is congruency between training and testing times. This review provides recommendations to improve the design and execution of future studies on this topic. REGISTRATION: PROSPERO (CRD42021246468).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.