Evidence mapPaperPMID 37208462Full record

SynthesisSports medicine - open2023

Best Time of Day for Strength and Endurance Training to Improve Health and Performance? A Systematic Review with Meta-analysis.

Fabienne Bruggisser, Raphael Knaier, Ralf Roth, Wei Wang, Jingyi Qian, Frank A J L Scheer

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Sports medicine - open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601660 (Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06601660 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Combined Physical Training At Different Times of the Day on Muscle and Adipose Tissue Remodeling, Metabolism and Physical Performance in Female Mice and Women with Obesity

TypeinterventionalSponsorState University of Minas GeraisRan2024 to 2025Enrolled60ConditionsObesity Type I and II, Obesity and OverweightArmsMorning Physical Training, Night Physical Training, No intervention
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
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  6. Review
  7. Article
  8. Article
  9. Exercise benefits in metabolism on cardiovascular disease.Frontiers in cardiovascular medicine · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fabienne Bruggisser *Department of Sport, Exercise and Health, Faculty of Medicine, University of Basel, Basel, Switzerland.
Raphael Knaier *Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA. raphael.knaier@unibas.ch.ORCID http://orcid.org/0000-0002-0244-7768
Ralf RothDepartment of Sport, Exercise and Health, Faculty of Medicine, University of Basel, Basel, Switzerland.
Wei WangDivision of Sleep Medicine, Harvard Medical School, Boston, MA, USA.
Jingyi Qian *Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-8793-9330
Frank A J L Scheer *Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA. fscheer@bwh.harvard.edu.ORCID https://orcid.org/0000-0002-2014-7582

Funding

Role of Meal Timing in Efficacy of Bariatric Surgery in Obese IndividualsR01HL140574 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRANK A SCHEER, Ali Tavakkoli · 2021 to 2023
$2.6M
Foundation for the National Institutes of Health K99HL148500Foundation for the National Institutes of Health R01DK102696Foundation for the National Institutes of Health R01DK105072Foundation for the National Institutes of Health R01HL140574NHLBI NIH HHS R01 HL140574Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung P2BSP3_191755Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PZ00P3_208999
6 · The paper itself

Abstract

backgroundCurrent recommendations for physical exercise include information about the frequency, intensity, type, and duration of exercise. However, to date, there are no recommendations on what time of day one should exercise. The aim was to perform a systematic review with meta-analysis to investigate if the time of day of exercise training in intervention studies influences the degree of improvements in physical performance or health-related outcomes.

methodsThe databases EMBASE, PubMed, Cochrane Library, and SPORTDiscus were searched from inception to January 2023. Eligibility criteria were that the studies conducted structured endurance and/or strength training with a minimum of two exercise sessions per week for at least 2 weeks and compared exercise training between at least two different times of the day using a randomized crossover or parallel group design.

resultsFrom 14,125 screened articles, 26 articles were included in the systematic review of which seven were also included in the meta-analyses. Both the qualitative synthesis and the quantitative synthesis (i.e., meta-analysis) provide little evidence for or against the hypothesis that training at a specific time of day leads to more improvements in performance-related or health-related outcomes compared to other times. There was some evidence that there is a benefit when training and testing occur at the same time of day, mainly for performance-related outcomes. Overall, the risk of bias in most studies was high.

conclusionsThe current state of research provides evidence neither for nor against a specific time of the day being more beneficial, but provides evidence for larger effects when there is congruency between training and testing times. This review provides recommendations to improve the design and execution of future studies on this topic. REGISTRATION: PROSPERO (CRD42021246468).

Indexed as

CardiovascularChronotypeCircadianDiurnalEnduranceMeta-analysisMetabolicPerformanceStrengthSystematic review

Identifiers

PMID37208462
PMCPMC10198889

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.