Evidence map›Paper›PMID 37208696›Full record

ArticleBiotechnology for biofuels and bioproducts2023

Transcriptomic and metabolomic analyses revealed regulation mechanism of mixotrophic Cylindrotheca sp. glycerol utilization and biomass promotion.

Song Wang, Xiyi Zhou, Sha Wu, Mengkai Zhao, Zhangli Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology for biofuels and bioproducts, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Song WangGuangdong Technology Research Center for Marine Algal Bioengineering; Guangdong Provincial Key Laboratory for Plant Epigenetics; Shenzhen Engineering Laboratory for Marine Algal Biotechnology; Longhua Innovation Institute for Biotechnology; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, China.
Xiyi ZhouGuangdong Technology Research Center for Marine Algal Bioengineering; Guangdong Provincial Key Laboratory for Plant Epigenetics; Shenzhen Engineering Laboratory for Marine Algal Biotechnology; Longhua Innovation Institute for Biotechnology; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, China.
Sha WuGuangdong Technology Research Center for Marine Algal Bioengineering; Guangdong Provincial Key Laboratory for Plant Epigenetics; Shenzhen Engineering Laboratory for Marine Algal Biotechnology; Longhua Innovation Institute for Biotechnology; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, China.
Mengkai ZhaoGuangdong Technology Research Center for Marine Algal Bioengineering; Guangdong Provincial Key Laboratory for Plant Epigenetics; Shenzhen Engineering Laboratory for Marine Algal Biotechnology; Longhua Innovation Institute for Biotechnology; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, China.
Zhangli HuGuangdong Technology Research Center for Marine Algal Bioengineering; Guangdong Provincial Key Laboratory for Plant Epigenetics; Shenzhen Engineering Laboratory for Marine Algal Biotechnology; Longhua Innovation Institute for Biotechnology; College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, China. huzl@szu.edu.cn.
Institute of Marine Biotechnology · DEInstitute for Learning Innovation · USShenzhen University · CN

Funding

Department of Education of Guangdong Province 2022KQNCX065Guangdong Key R & D Project 2022B1111070005Ministry of Science and Technology of the People's Republic of China 2018YFA0902500National Natural Science Foundation of China 32273118Shenzhen Special Fund for Sustainable Development KCXFZ20211020164013021Shenzhen University 2035 Initiative 2022B010the Key Laboratory of Mariculture of Ministry of Education, Ocean University of China KLM202204
6 · The paper itself

Abstract

backgroundDiatoms have been viewed as ideal cell factories for production of some high-value bioactive metabolites, such as fucoxanthin, but their applications are restrained by limited biomass yield. Mixotrophy, by using both CO

resultsGlycerol, among tested carbon sources, was proved as the sole that could significantly promote growth of Cylindrotheca sp. with illumination, a so-called growth pattern, mixotrophy. Biomass and fucoxanthin yields of Cylindrotheca sp., grown in medium with glycerol (2 g L

conclusionsConclusively, this study not only provides an alternative for large-scale cultivation of Cylindrotheca, but also pinpoints the limiting enzymes subject to further metabolic manipulation. Most importantly, the novel insights in this study should aid to understand the mechanism of biomass promotion in mixotrophic Cylindrotheca sp.

Indexed as

BiomassCylindrothecaDiatomFucoxanthinMetabolomeMixotrophyTranscriptome

Identifiers

PMID37208696
PMCPMC10199484
OpenAlexW4377116146

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.