Evidence map›Paper›PMID 37210756›Full record

ArticleGrowth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society

Growth hormone-releasing hormone antagonists counteract hydrogen peroxide - induced paracellular hyperpermeability in endothelial cells.

Nektarios Barabutis, Agnieszka Siejka, Mohammad S Akhter

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Growth hormone - releasing hormone in the immune system.Reviews in endocrine & metabolic disorders · 2025
    Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Nektarios BarabutisSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA. Electronic address: barabutis@ulm.edu.
Agnieszka SiejkaDepartment of Clinical Endocrinology, Medical University of Lodz, Lodz, Poland.
Mohammad S AkhterSchool of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.
University of Louisiana at Monroe · USMedical University of Lodz · PL

Funding

Molecular and Cell Biology Resources CoreP20GM103424 · LOUISIANA STATE UNIV A&M COL BATON ROUGE · 2025 to 2025
$4.1M
NIGMS NIH HHS P20 GM103424
6 · The paper itself

Abstract

Growth Hormone-Releasing Hormone (GHRH) is a hypothalamic peptide which regulates the release of Growth Hormone from the anterior pituitary gland, and has been involved in inflammatory processes. On the other hand, GHRH antagonists (GHRHAnt) were developed to counteract those effects. Herein we demonstrate for the first time that GHRHAnt can suppress hydrogen peroxide (H

Indexed as

Endothelial CellsHydrogen PeroxideAnimalsCattleGrowth HormoneGrowth Hormone-Releasing HormoneLungGrowth HormoneGrowth Hormone-Releasing HormoneHydrogen PeroxideBarrier functionEndotheliumLung injury

Identifiers

PMID37210756
PMCPMC10247445
OpenAlexW4377019736

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.