Evidence mapPaperPMID 37213800Full record

ArticleEuropean heart journal supplements : journal of the European Society of Cardiology2023

ANMCO position paper on the management of hypercholesterolaemia in patients with acute coronary syndrome.

Leonardo De Luca, Carmine Riccio, Alessandro Navazio, Serafina Valente, Manlio Cipriani, Marco Corda, Alfredo De Nardo, Giuseppina Maura Francese, Cosimo Napoletano, Emanuele Tizzani and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal supplements : journal of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07252388 (Educational Intervention for Patient's Awareness on eaRly LDL-C Lowering Using Novel Pharmacological Strategies in secondarY Prevention), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07252388 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Educational Intervention for Patient's Awareness on eaRly LDL-C Lowering Using Novel Pharmacological Strategies in secondarY Prevention (EARLY)

TypeinterventionalSponsorHeart Care FoundationRan2025 to 2027Enrolled240ConditionsAcute Coronary Syndromes, Chronic Coronary SyndromesArmsPatient-oriented educational intervention
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Leonardo De LucaDipartimento di Scienze Cardio-Toraco-Vascolari, UOC Cardiologia, AO San Camillo-Forlanini, Circonvallazione Gianicolense, 87, 00152 Roma, Italy.ORCID https://orcid.org/0000-0002-8552-1272
Carmine RiccioUOSD Follow-up del Paziente Post-Acuto, Dipartimento Cardio-Vascolare, AORN Sant'Anna e San Sebastiano, Caserta 81100, Italy.
Alessandro NavazioSOC Cardiologia Ospedaliera, Presidio Ospedaliero Arcispedale Santa Maria Nuova, Azienda USL di Reggio Emilia-IRCCS, Reggio Emilia 42121, Italy.
Serafina ValenteDipartimento Cardio-Toracico, AOU Senese, Ospedale Santa Maria alle Scotte, Siena 53100, Italy.
Manlio CiprianiUOC Cardiologia, ISMETT (Istituto Mediterraneo per i Trapianti e Terapie ad alta specializzazione), Palermo 90121, Italy.
Marco CordaS.C. Cardiologia, Azienda Ospedaliera G. Brotzu, Cagliari 09121, Italy.
Alfredo De NardoUO Cardiologia-UTIC, Ospedale Civile 'G. Jazzolino', Vibo Valentia 89900, Italy.
Giuseppina Maura FranceseUOC Cardiologia, Ospedale Garibaldi-Nesima, Azienda di Rilievo Nazionale e Alta Specializzazione 'Garibaldi', Catania 95100, Italy.
Cosimo NapoletanoUOC Cardiologia-UTIC-Emodinamica, Presidio Ospedaliero 'G. Mazzini', Teramo 64100, Italy.
Emanuele TizzaniDipartimento di Cardiologia, Ospedale degli Infermi, Rivoli (TO), Torino 10098, Italy.
Loris RonconUOC Cardiologia, Ospedale Santa Maria della Misericordia, Rovigo 45100, Italy.
Pasquale CaldarolaUOC Cardiologia-UTIC, AO Ospedale San Paolo, Bari 70100, Italy.
Michele Massimo GuliziaUOC Cardiologia, Ospedale Garibaldi-Nesima, Azienda di Rilievo Nazionale e Alta Specializzazione 'Garibaldi', Catania 95100, Italy.
Domenico GabrielliDipartimento di Scienze Cardio-Toraco-Vascolari, UOC Cardiologia, AO San Camillo-Forlanini, Circonvallazione Gianicolense, 87, 00152 Roma, Italy.
Fabrizio OlivaUnità di Cure Intensive Cardiologiche, Cardiologia 1-Emodinamica, Dipartimento Cardiotoracovascolare 'A. De Gasperis', ASST Grande Ospedale Metropolitano Niguarda, Milano 20162, Italy.
Furio ColivicchiUOC Cardiologia Clinica e Riabilitativa, Presidio Ospedaliero San Filippo Neri-ASL Roma 1, Roma 00176, Italia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients suffering from acute coronary syndrome (ACS) present a high risk of recurrence and new adverse cardiovascular events after hospital discharge. Elevated plasma LDL-cholesterol (LDL-C) levels have been shown to be a causal factor for the development of coronary heart disease, and robust clinical evidence has documented that LDL-C levels decrease linearly correlates with a reduction in cardiovascular events. Recent studies have also demonstrated the safety and efficacy of an early and significant reduction in LDL-C levels in patients with ACS. In this position paper, Italian Association of Hospital Cardiologists proposes a decision algorithm on early adoption of lipid-lowering strategies at hospital discharge and short-term follow-up of patients with ACS, in the light of the multiple evidence generated in recent years on the treatment of hypercholesterolaemia and the available therapeutic options, considering current reimbursement criteria.

Indexed as

Acute coronary syndromeBempedoic acidEzetimibeFast-trackHypercholesterolaemiaPCSK9 inhibitorsStatinsVery high risk

Identifiers

PMID37213800
PMCPMC10194822

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.