Evidence map›Paper›PMID 37214830›Full record

ArticlebioRxiv : the preprint server for biology2024

Influence of expression and purification protocols on Gα biochemical activity: kinetics of plant and mammalian G protein cycles.

Timothy E Gookin, David Chakravorty, Sarah M Assmann

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Timothy E GookinBiology Department, Pennsylvania State University, University Park, Pennsylvania 16802.ORCID 0000-0002-0994-0790
David ChakravortyBiology Department, Pennsylvania State University, University Park, Pennsylvania 16802.ORCID 0000-0002-6591-4853
Sarah M AssmannBiology Department, Pennsylvania State University, University Park, Pennsylvania 16802.ORCID 0000-0003-4541-1594
Pennsylvania State University · US

Funding

Regulation of heterotrimeric G protein signaling by subunit phosphorylationR01GM126079 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI ASSMANN, SARAH M · 2018 to 2022
$1.5M
Phospho- and natural-variant regulation of heterotrimeric G protein signalingR35GM153492 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Sarah M Assmann · 2024 to 2026
$1.2M
NIGMS NIH HHS R01 GM126079NIGMS NIH HHS R35 GM153492
6 · The paper itself

Abstract

Heterotrimeric G proteins are a class of signal transduction complexes with broad roles in human health and agriculturally important plant traits. In the classic paradigm, guanine nucleotide binding to the Gα subunit regulates the activation status of the complex. Using the

Indexed as

BODIPYDomain swapGNAI1GNAO1GPA1GTPGTPaseHeterotrimeric G proteinRecombinant protein expressionSYPRO Orange

Identifiers

PMID37214830
PMCPMC10197700
OpenAlexW4376140882

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.