Evidence map›Paper›PMID 37215219›Full record

ArticleFrontiers in nutrition2023

Impact of

Susan Sergeant, Brian A Keith, Michael C Seeds, Jimaree A Legins, Caroline B Young, Mara Z Vitolins, Floyd H Chilton

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Frontiers in nutrition · 2026
    Article
  4. Metabolites · 2025
    Article
  5. Article
  6. Fatty acid desaturase genetic variations in heart failure and cardiovascular disease.American heart journal plus : cardiology research and practice · 2025
    Review
  7. The influence ofFrontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Susan SergeantDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Brian A KeithDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Michael C SeedsWake Forest Institute for Regenerative Medicine, Winston-Salem, NC, United States.
Jimaree A LeginsDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Caroline B YoungDepartment of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Mara Z VitolinsDepartment of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, United States.
Floyd H ChiltonSchool of Nutritional Sciences and Wellness, University of Arizona, Tucson, AZ, United States.
Wake Forest University · USForest Institute · USUniversity of Arizona · US

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Role of PUFA-Gene Interactions in Health DisparitiesR01AT008621 · NCCIH · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI FLOYD H CHILTON, Susan Schembre · 2016 to 2026
$5.4M
NCATS NIH HHS UL1 TR001420NCCIH NIH HHS R01 AT008621
6 · The paper itself

Abstract

Introduction: Polyunsaturated fatty acids (PUFA) and highly unsaturated fatty acid (HUFA) synthetic products and their signaling metabolites play vital roles in immunity, inflammation, and brain development/function. Frequency differences of variants within the fatty acid desaturase ( Methods: Data and biospecimens (plasma, red blood cells, buffy coat-derived DNA) from 135 participants (83.7% female) were used to assess the relationship(s) between dietary PUFA levels, a Results: The dietary habits of the cohort showed that participant diets contained a high ratio (9.3 ± 0.2, mean ± SEM) of linoleic acid ( Discussion: Taken together, this study illustrates that dietary PUFA + HUFA ×

Indexed as

dietFADS clusterhighly unsaturated fatty acidHispanic (demographic)HUFALatino (Hispanic)omega-3 HUFA deficiencyPUFA

Identifiers

PMID37215219
PMCPMC10196633
OpenAlexW4377564425

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.