Evidence map›Paper›PMID 37215546›Full record

ArticleFrontiers in cardiovascular medicine2023

The efficacy of therapeutic plasma exchange in COVID-19 patients on endothelial tightness

Theo Ebermeyer, Olivier Hequet, Frederic Berard, Amelie Prier, Marie-Ange Eyraud, Charles-Antoine Arthaud, Marco Heestermans, Anne-Claire Duchez, Aurelie Guironnet-Paquet, Philippe Berthelot and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Theo EbermeyerINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Olivier HequetEtablissement Français du Sang Auvergne-Rhône-Alpes, Research Department, F-42023, Saint-Etienne, France.
Frederic BerardCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS, UMR5308, ENS Lyon, UJM, Université Claude Bernard Lyon 1, Université Jean Monnet de Saint-Etienne, Lyon, France.
Amelie PrierINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Marie-Ange EyraudINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Charles-Antoine ArthaudINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Marco HeestermansINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Anne-Claire DuchezINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Aurelie Guironnet-PaquetEtablissement Français du Sang Auvergne-Rhône-Alpes, Research Department, F-42023, Saint-Etienne, France.
Philippe BerthelotCIRI-Centre International de Recherche en Infectiologie, Inserm, U1111, CNRS, UMR5308, ENS Lyon, UJM, Université Claude Bernard Lyon 1, Université Jean Monnet de Saint-Etienne, Lyon, France.
Fabrice CognasseINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Hind Hamzeh-CognasseINSERM, U 1059 SAINBIOSE, Université Jean Monnet, Mines Saint-Étienne, F-42023, Saint-Etienne, France.
Établissement Français du Sang · FRUniversité Jean Monnet · FRBiologie, ingénierie et imagerie pour l'Ophtalmologie · FRInserm · FRCentre International de Recherche en Infectiologie · FRMines Saint-Étienne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease (COVID)-19 is characterised in particular by vascular inflammation with platelet activation and endothelial dysfunction. During the pandemic, therapeutic plasma exchange (TPE) was used to reduce the cytokine storm in the circulation and delay or prevent ICU admissions. This procedure consists in replacing the inflammatory plasma by fresh frozen plasma from healthy donors and is often used to remove pathogenic molecules from plasma (autoantibodies, immune complexes, toxins, etc.). This study uses an

Indexed as

COVID-19endotheliuminflammationplatelettherapeutic plasma exchange

Identifiers

PMID37215546
PMCPMC10192624
OpenAlexW4368368088

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.