Evidence map›Paper›PMID 37219463›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2023

Myeloid vitamin D receptor regulates Paneth cells and microbial homeostasis.

Danika S Bakke, Jilei Zhang, Yongguo Zhang, Destiny Ogbu, Yinglin Xia, Jun Sun

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Danika S BakkeDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Jilei ZhangDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Yongguo ZhangDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Destiny OgbuDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Yinglin XiaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.
Jun SunDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois Chicago, Chicago, Illinois, USA.ORCID 0000-0001-7465-3133
University of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

How Vitamin D Receptor Influences Intestinal BarriersR01DK114126 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Jun Sun · 2018 to 2026
$3.0M
UIC Portal to Biomedical Research Careers (UIC PBRC) PREPR25GM121212 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALFONSO, AIXA, FEDERLE, MICHAEL J · 2018 to 2024
$1.8M
Vitamin D Receptor Regulation of Microbiota in Intestinal EpitheliaR01DK105118 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUN, JUN · 2016 to 2020
$1.8M
Microbiome and intestinal barrier in ALS therapyI01BX004824 · VA · JESSE BROWN VA MEDICAL CENTER · PI SUN, JUN · 2020 to 2025
–
BLRD VA I01 BX004824NIDDK NIH HHS R01 DK105118NIDDK NIH HHS R01 DK114126NIGMS NIH HHS R25 GM121212
6 · The paper itself

Abstract

Cross talk between immune cells and the intestinal crypt is critical in maintaining intestinal homeostasis. Recent studies highlight the direct impact of vitamin D receptor (VDR) signaling on intestinal and microbial homeostasis. However, the tissue-specific role of immune VDR signaling is not fully understood. Here, we generated a myeloid-specific VDR knockout (VDR

Indexed as

Paneth CellsReceptors, CalcitriolAnimalsEpitheliumHomeostasisMiceSignal TransductionReceptors, CalcitriolBeta-catenincolitisepithelial biologyimmunityPaneth cellsVDRWnt signaling

Identifiers

PMID37219463
PMCPMC10321143
OpenAlexW4377565636

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.