Evidence map›Paper›PMID 37220313›Full record

ReviewAnnual review of genomics and human genetics2023

Methods for Assessing Population Relationships and History Using Genomic Data.

Priya Moorjani, Garrett Hellenthal

Abstract readReview
In one paragraph

Review in Annual review of genomics and human genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Priya MoorjaniDepartment of Molecular and Cell Biology and Center for Computational Biology, University of California, Berkeley, California, USA; email: moorjani@berkeley.edu.
Garrett HellenthalUCL Genetics Institute and Research Department of Genetics, Evolution, and Environment, University College London, London, United Kingdom; email: g.hellenthal@ucl.ac.uk.

Funding

Genomic Insights into Human Population Mixture and its Role in Adaptation and DiseaseR35GM142978 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Priya Moorjani · 2021 to 2026
$2.5M
Department of HealthNIGMS NIH HHS R35 GM142978Wellcome TrustWellcome Trust 098386/Z/12/ZWellcome Trust 224575/Z/21/Z
6 · The paper itself

Abstract

Genetic data contain a record of our evolutionary history. The availability of large-scale datasets of human populations from various geographic areas and timescales, coupled with advances in the computational methods to analyze these data, has transformed our ability to use genetic data to learn about our evolutionary past. Here, we review some of the widely used statistical methods to explore and characterize population relationships and history using genomic data. We describe the intuition behind commonly used approaches, their interpretation, and important limitations. For illustration, we apply some of these techniques to genome-wide autosomal data from 929 individuals representing 53 worldwide populations that are part of the Human Genome Diversity Project. Finally, we discuss the new frontiers in genomic methods to learn about population history. In sum, this review highlights the power (and limitations) of DNA to infer features of human evolutionary history, complementing the knowledge gleaned from other disciplines, such as archaeology, anthropology, and linguistics.

Indexed as

ArchaeologyGenomicsAnthropologyBiological EvolutionHuman Genome ProjectHumansadmixtureancestrydemographic inferenceeffective population sizemolecular clocks

Identifiers

PMID37220313
PMCPMC11040641

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.