Evidence map›Paper›PMID 37221849›Full record

ArticleProceedings. Biological sciences2023

Liver transcriptomic and methylomic analyses identify transcriptional mitogen-activated protein kinase regulation in facultative hibernation of Syrian hamster.

Louis Coussement, Marloes M Oosterhof, Victor Guryev, Vera A Reitsema, Jojanneke J Bruintjes, Maaike Goris, Hjalmar R Bouma, Tim de Meyer, Marianne G Rots, Robert H Henning

Open access · greenAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Exposure to Dim Light at Night Impairs Photoperiodic and Metabolic Gene Expression in Syrian Hamsters (Mesocricetus auratus).Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Viruses · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Louis CoussementDepartment of Data Analysis and Mathematical Modelling, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium.ORCID 0000-0003-1736-4962
Marloes M OosterhofDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Victor GuryevEuropean Research Institute for the Biology of Ageing, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Vera A ReitsemaDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Jojanneke J BruintjesDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Maaike GorisDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Hjalmar R BoumaDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Tim de MeyerDepartment of Data Analysis and Mathematical Modelling, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium.
Marianne G RotsDepartment of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Robert H HenningDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
University Medical Center Groningen · NLGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hibernation consists of alternating torpor-arousal phases, during which animals cope with repetitive hypothermia and ischaemia-reperfusion. Due to limited transcriptomic and methylomic information for facultative hibernators, we here conducted RNA and whole-genome bisulfide sequencing in liver of hibernating Syrian hamster (

Indexed as

HibernationTranscriptomeAnimalsCricetinaeGene Expression ProfilingLiverMesocricetuscell cycleDNA methylationfacultative hibernatorgene regulationtorportranscription factor-binding sites

Identifiers

PMID37221849
PMCPMC10206468
OpenAlexW4377939882

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.