Evidence map›Paper›PMID 37227089›Full record

ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2023

Future research directions of the model marine tubeworm Hydroides elegans and synthesis of developmental staging of the complete life cycle.

Katherine T Nesbit, Nicholas J Shikuma

Abstract read
In one paragraph

Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. MyD88 knockdown by RNAi prevents bacterial stimulation of tubeworm metamorphosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katherine T NesbitDepartment of Biology, San Diego State University, San Diego, California, USA.ORCID 0000-0003-3437-7511
Nicholas J ShikumaDepartment of Biology, San Diego State University, San Diego, California, USA.ORCID 0000-0001-5518-5020

Funding

Examining a Unique Contractile Injection System Mediating Host-Microbe InteractionsR35GM146722 · NIGMS · SAN DIEGO STATE UNIVERSITY · PI Nicholas J Shikuma · 2022 to 2026
$1.9M
NIGMS NIH HHS R35 GM146722NIGMS NIH HHS R35GM146722
6 · The paper itself

Abstract

backgroundThe biofouling marine tube worm, Hydroides elegans, is an indirect developing polychaete with significance as a model organism for questions in developmental biology and the evolution of host-microbe interactions. However, a complete description of the life cycle from fertilization through sexual maturity remains scattered in the literature, and lacks standardization. RESULTS AND DISCUSSION: Here, we present a unified staging scheme synthesizing the major morphological changes that occur during the entire life cycle of the animal. These data represent a complete record of the life cycle, and serve as a foundation for connecting molecular changes with morphology.

conclusionsThe present synthesis and associated staging scheme are especially timely as this system gains traction within research communities. Characterizing the Hydroides life cycle is essential for investigating the molecular mechanisms that drive major developmental transitions, like metamorphosis, in response to bacteria.

Indexed as

BiofoulingPolychaetaAnimalsLarvaLife Cycle StagesMetamorphosis, BiologicalbacteriadevelopmentHydroides elegansmetamorphosis

Identifiers

PMID37227089
PMCPMC10674040

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.