ArticleAnnals of medicine and surgery (2012)2023
Gut-brain axis: altered microbiome and depression - review.
Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Trial
- Microbiome-Inflammation-Mitochondria Coupling in Neurodegeneration and Depression: An Integrative Opinion.Molecular neurobiology · 2026Review
- Maternal Diet Quality and Third Trimester Depression: Insights From a Nepali Birth Cohort Study.Maternal & child nutrition · 2026Article
- Research progress and controversies in the treatment of functional constipation-related depression with probiotics and prebiotics: a narrative review.Frontiers in pharmacology · 2026Review
- The Role and Mechanisms of Probiotic Supplementation on Depressive Symptoms: A Narrative Review.Current nutrition reports · 2025Review
- Anxiolytic, Antidepressant and Healthy Sleep-Promoting Potential of Rosmarinic Acid: Mechanisms and Molecular Targets.Neuropsychiatric disease and treatment · 2025Review
- Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota.CNS & neurological disorders drug targets · 2025Article
- Rosacea in Older Adults and Pharmacologic Treatments.Drugs & aging · 2024Review
- The Impact of Early-Life Cecal Microbiota Transplantation on Social Stress and Injurious Behaviors in Egg-Laying Chickens.Microorganisms · 2024Review
- Role of Probiotics and Prebiotics in Gut Symbiosis.Nutrients · 2024Article
- Microbiota-Based Live Biotherapeutic Products forInfection and drug resistance · 2024Review
- Unveiling the Connection between Microbiota and Depressive Disorder through Machine Learning.International journal of molecular sciences · 2023Article
- Research advances on the pathogenesis and clinical interventions of post-stroke depression.Frontiers in neurologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concept of a 'gut-brain axis' was recently developed when the complex communications between the brain and the gut became evident. The interaction may affect emotions, motivation, mood, and higher cognitive functions as well as gut homeostasis. Human microbe symbiosis's merits are now acknowledged to transcend human mental health. Research has recently indicated that the gut-brain axis plays a vital role in brain health maintenance. The term 'gut-brain axis' can only partially capture the intricacy of these interactions. Dysbiosis of the gut commensals has been seen in patients with psychiatric diseases, such as depression. Major depressive disorder is caused by complicated interactions between the individual gene and the environment. In a forced swimming test, P. Zheng
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.