Evidence map›Paper›PMID 37230379›Full record

ArticleJournal of molecular and cellular cardiology2023

Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term.

Hector Chapoy Villanueva, Jae Hwi Sung, Jackie A Stevens, Michael J Zhang, Peyton M Nelson, Lalitha S Denduluri, Feng Feng, Timothy D O'Connell, DeWayne Townsend, Julia C Liu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. MICU proteins facilitate CaResearch square · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. MCU-independent CaScientific reports · 2024
    Article
  14. Mechanisms of reduced myocardial energetics of the dystrophic heart.American journal of physiology. Heart and circulatory physiology · 2024
    Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hector Chapoy VillanuevaDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Jae Hwi SungDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Jackie A StevensDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Michael J ZhangDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA; Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Peyton M NelsonDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Lalitha S DenduluriDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Feng FengDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Timothy D O'ConnellDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
DeWayne TownsendDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Julia C LiuDepartment of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA. Electronic address: julialiu@umn.edu.
University of Minnesota Medical Center · US

Funding

Modulating mitochondrial calcium in cardiac homeostasis and diseaseR01HL164491 · NHLBI · UNIVERSITY OF MINNESOTA · PI Julia Chang Liu · 2022 to 2026
$2.2M
Molecular mechanism and physiological function of mitochondrial calcium regulationK22HL137901 · NHLBI · UNIVERSITY OF MINNESOTA · PI LIU, JULIA CHANG · 2020 to 2022
$747k
NHLBI NIH HHS K22 HL137901NHLBI NIH HHS R01 HL164491
6 · The paper itself

Abstract

Transport of Ca

Indexed as

Calcium ChannelsMitochondrial MembranesAdenosine TriphosphateAnimalsCalciumMiceMitochondria, HeartMitochondrial ProteinsAdenosine TriphosphateCalciumCalcium ChannelsEmre protein, mouseMcu protein, mousemitochondrial calcium uniporterMitochondrial ProteinsATPCalciumIschemia/reperfusionMitochondriaMitochondrial calcium uniporterPermeability transition pore

Identifiers

PMID37230379
PMCPMC10524693
OpenAlexW4377694822

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.