Evidence map›Paper›PMID 37233187›Full record

ReviewJournal of cardiovascular development and disease2023

Positron Emission Tomography in Heart Failure: From Pathophysiology to Clinical Application.

Gregorio Tersalvi, Vittorio Beltrani, Martin R Grübler, Alessandra Molteni, Yvonne Cristoforetti, Giovanni Pedrazzini, Giorgio Treglia, Luigi Biasco

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07243119 (PRIMA-HF PRedicting Recovery of Left Ventricular Function With Multimodality Cardiac IMAging in Patients With de Novo Heart Failure HAI-HF), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07243119 phase4enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

PRIMA-HF PRedicting Recovery of Left Ventricular Function With Multimodality Cardiac IMAging in Patients With de Novo Heart Failure HAI-HF: High-Dose Adenosine During Perfusion Imaging in Heart Failure: Rationale and Design of the HAI-HF Trial

TypeinterventionalSponsorGødstrup HospitalRan2025 to 2029Enrolled180ConditionsHeart Failure and Reduced Ejection Fraction, Heart FailureArmsHAI-HF: Adenosine Stress [¹⁵O]H₂O PET Imaging, Two different doses of adenosine
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Mitochondrial Dysfunction in Diabetes: Shedding Light on a Widespread Oversight.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Gregorio TersalviDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.ORCID 0000-0003-1845-1777
Vittorio BeltraniDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Martin R GrüblerDepartment of Cardiology, Regional Hospital Neustadt, 2700 Wiener Neustadt, Austria.ORCID 0000-0002-1761-2914
Alessandra MolteniDepartment of Internal Medicine, Ente Ospedaliero Cantonale, 6850 Mendrisio, Switzerland.
Yvonne CristoforettiFaculty of Biomedical Sciences, Università della Svizzera Italiana (USI), 6900 Lugano, Switzerland.
Giovanni PedrazziniDepartment of Cardiology, Cardiocentro Ticino Institute, Ente Ospedaliero Cantonale, 6900 Lugano, Switzerland.
Giorgio TregliaFaculty of Biomedical Sciences, Università della Svizzera Italiana (USI), 6900 Lugano, Switzerland.ORCID 0000-0001-9808-780X
Luigi BiascoFaculty of Biomedical Sciences, Università della Svizzera Italiana (USI), 6900 Lugano, Switzerland.
Ente Ospedaliero Cantonale · CHASL Roma · ITMedical University of Graz · ATUniversità della Svizzera italiana · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging modalities are increasingly being used to evaluate the underlying pathophysiology of heart failure. Positron emission tomography (PET) is a non-invasive imaging technique that uses radioactive tracers to visualize and measure biological processes in vivo. PET imaging of the heart uses different radiopharmaceuticals to provide information on myocardial metabolism, perfusion, inflammation, fibrosis, and sympathetic nervous system activity, which are all important contributors to the development and progression of heart failure. This narrative review provides an overview of the use of PET imaging in heart failure, highlighting the different PET tracers and modalities, and discussing fields of present and future clinical application.

Indexed as

heart failuremetabolic imagingmicrovascular dysfunctionPETradionuclide

Identifiers

PMID37233187
PMCPMC10218989
OpenAlexW4377108300

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.