Evidence map›Paper›PMID 37233703›Full record

ArticleMetabolites2023

Bone Metabolite Profile Differs between Normal and Femur Head Necrosis (FHN/BCO)-Affected Broilers: Implications for Dysregulated Metabolic Cascades in FHN Pathophysiology.

Alison Ramser, Rachel Hawken, Elizabeth Greene, Ron Okimoto, Brenda Flack, Courtney J Christopher, Shawn R Campagna, Sami Dridi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alison RamserCenter of Excellence for Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA.
Rachel HawkenCobb-Vantress, Siloam Springs, AR 72761, USA.
Elizabeth GreeneCenter of Excellence for Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA.
Ron OkimotoCobb-Vantress, Siloam Springs, AR 72761, USA.
Brenda FlackCobb-Vantress, Siloam Springs, AR 72761, USA.
Courtney J ChristopherDepartment of Chemistry, University of Tennessee, Knoxville, TN 37996, USA.
Shawn R CampagnaDepartment of Chemistry, University of Tennessee, Knoxville, TN 37996, USA.
Sami DridiCenter of Excellence for Poultry Science, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0002-6441-2560

Funding

Cobb-Vantress, Inc RAC
6 · The paper itself

Abstract

Femur head necrosis (FHN), also known as bacterial chondronecrosis with osteomyelitis (BCO), has remained an animal welfare and production concern for modern broilers regardless of efforts to select against it in primary breeder flocks. Characterized by the bacterial infection of weak bone, FHN has been found in birds without clinical lameness and remains only detectable via necropsy. This presents an opportunity to utilize untargeted metabolomics to elucidate potential non-invasive biomarkers and key causative pathways involved in FHN pathology. The current study used ultra-performance liquid chromatography coupled with high-resolution mass spectrometry (UPLC-HRMS) and identified a total of 152 metabolites. Mean intensity differences at

Indexed as

bacterial chondronecrosis with osteomyelitisbroilerfemur head necrosismetabolome

Identifiers

PMID37233703
PMCPMC10223080

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.