ArticleFrontiers in microbiology2023
Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes.
Erratum issuedAbstract read
In one paragraph
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Development of dihydroquinazoline compounds as novel therapeutics against Naegleria fowleri.Bioorganic & medicinal chemistry letters · 2025Article
- Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living AmoebaJournal of natural products · 2025Article
- Synthesis and Evaluation of Benzylamine Inhibitors of NeuropathogenicACS medicinal chemistry letters · 2024Article
- Phenotypic assay for cytotoxicity assessment ofFrontiers in microbiology · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
31 authors.
Lori FerrinsDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Melissa J BuskesDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Madison M KapteynCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Hannah N EngelsCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Suzanne E EnosCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Chenyang LuDepartment of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, United States.
Dana M KlugDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Baljinder SinghDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Antonio QuotadamoDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Kelly BachovchinDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Westley F TearDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Andrew E SpauldingDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Katherine C ForbesDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Seema BagDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Mitch RiversDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Catherine LeBlancDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Erin BurchfieldDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Jeremy R ArmandDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Rosario Diaz-GonzalezInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Gloria Ceballos-PerezInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Raquel García-HernándezInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Guiomar Pérez-MorenoInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Cristina Bosch-NavarreteInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Luis Miguel Ruiz-PérezInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Francisco GamarroInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Dolores González-PacanowskaInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Miguel NavarroInstituto de Parasitología y Biomedicina "López-Neyra" Consejo Superior de Investigaciones Científicas (CSIC), Granada, Spain.
Kojo Mensa-WilmotDepartment of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, GA, United States.
Michael P PollastriDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA, United States.
Dennis E KyleCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Christopher A RiceCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, United States.
Funding
Optimization and Modes of Action of NEU-4438, a New Anti-trypanosome Lead DrugR01AI124046 · NIAID · NORTHEASTERN UNIVERSITY · PI FERRINS, LORI, MENSA-WILMOT, KOJO A. · 2016 to 2025
$6.0MRepurposing human kinase inhibitor chemotypes for Neglected Tropical DiseasesR01AI114685 · NIAID · NORTHEASTERN UNIVERSITY · PI FERRINS, LORI · 2015 to 2025
$4.6MCuraxin-137, A New Lead for Anti-Trypanosome Drug Discovery - Resubmission - 1R01AI126311 · NIAID · UNIVERSITY OF GEORGIA · PI HAJDUK, STEPHEN L, POLLASTRI, MICHAEL P · 2017 to 2020
$2.7MLead optimization of hits identified from virtual and experimental screens of multiple industrial libraries DNDiR33AI141227 · NIAID · NORTHEASTERN UNIVERSITY · PI FERRINS, LORI · 2021 to 2023
$1.2MDefining the death transcriptome of Schistosoma mansoni to construct a molecular drug screenR21AI126296 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CAFFREY, CONOR · 2017 to 2018
$415kNIAID NIH HHS R01 AI114685NIAID NIH HHS R01 AI124046NIAID NIH HHS R01 AI126311NIAID NIH HHS R21 AI126296NIAID NIH HHS R33 AI141227
Abstract
PubMed holds no abstract for this paper.
Indexed as
Acanthamoeba speciesBalamuthia mandrillariscross-screeninghit-identificationkinase inhibitorsNaegleria fowleripathogenic free-living amoeba
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.