ArticleScience advances2023
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Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 31 citations in OpenAlex.
- Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer's tau pathology and uncover human-specific neuronal vulnerability.bioRxiv : the preprint server for biology · 2026Article
- Spatial Profiling of Glycosaminoglycans (GAGomics) From Laser Microdissected Mouse Brain.Molecular & cellular proteomics : MCP · 2026Article
- Brain vascular stability relies on PAK2-cilia-PDGF-BB-HSPGs on basolateral side of endothelium.Life science alliance · 2026Article
- Article
- RNA-binding protein PTBP1 mediates HSV-1 attachment and infection through regulation of heparan sulfate 3-O-sulfotransferase gene expression.Cell & bioscience · 2025Article
- Late-stage O-sulfation with a bioinspired sulfuryl donor.Nature communications · 2025Article
- 3-O Sulfated Heparan Sulfate (G2) Peptide Ligand Impairs the Infectivity ofBiomolecules · 2025Article
- Recent analytical advances in the detection and characterization of 3-O-sulfated heparan sulfate.Analytical and bioanalytical chemistry · 2025Review
- A synthetic HS structure selectively impairs the morphology and function of excitatory synapse by disrupting neurexin1 interactions.Glycobiology · 2025Article
- The pathogenic APP N-terminal Val225Ala mutation alters tau protein liquid-liquid phase separation and exacerbates synaptic damage.Molecular psychiatry · 2025Article
- Multi-omic analysis of meningeal cerebral amyloid angiopathy reveals enrichment of unsubstituted glucosamine and extracellular proteins.Journal of neuropathology and experimental neurology · 2025Article
- Untangling Heparan Sulfate 3-Analytical chemistry · 2025Article
- THE INTERACTION BETWEEN ANTITHROMBIN AND ENDOTHELIAL HEPARAN SULFATE MITIGATES PULMONARY THROMBOINFLAMMATION AFTER TRAUMA AND HEMORRHAGIC SHOCK.Shock (Augusta, Ga.) · 2025Article
- UtilizingAmerican journal of physiology. Cell physiology · 2025Review
- Genetic Markers of Postmortem Brain Iron.Journal of neurochemistry · 2025Article
- PITX2 expression and Neanderthal introgression in HS3ST3A1 contribute to variation in tooth dimensions in modern humans.Current biology : CB · 2025Article
- A novel TGFβ1-Hs3st2-tau axis regulates tau pathology and synaptic integrity.Frontiers in neuroscience · 2025Article
- Loss of 3-O-sulfotransferase enzymes, Hs3st3a1 and Hs3st3b1, reduces kidney and glomerular size and disrupts glomerular architecture.Matrix biology : journal of the International Society for Matrix Biology · 2024Article
- Multifaceted Heparin: Diverse Applications beyond Anticoagulant Therapy.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease.Molecular neurodegeneration · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 7 institutions in 1 country.
Zhangjie WangDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0003-4301-953X
Vaishali N PatelMatrix and Morphogenesis Section, National Institute of Dental and Craniofacial Research, NIH, DHHS, Bethesda, MD 20892, USA.
Xuehong SongDepartment of Molecular Pharmacology and Physiology, Byrd Alzheimer's Center and Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612 USA.
Yongmei XuDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0002-3756-581X
Andrea M KaminskiGenome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.ORCID 0000-0002-6263-4186
Vivien Uyen DoanDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0002-5536-4093
Guowei SuGlycan Therapeutics Corp., 617 Hutton Street, Raleigh, NC 27606, USA.ORCID 0000-0003-2668-9275
Yien LiaoDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0002-2114-8181
Dylan MahDepartment of Biological Sciences, Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.ORCID 0000-0002-7734-6101
Fuming ZhangDepartment of Biological Sciences, Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.ORCID 0000-0003-2803-3704
Vijayakanth PagadalaGlycan Therapeutics Corp., 617 Hutton Street, Raleigh, NC 27606, USA.ORCID 0000-0001-7349-4230
Chunyu WangDepartment of Biological Sciences, Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
Lars C PedersenGenome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.ORCID 0000-0002-4488-4077
Lianchun WangDepartment of Molecular Pharmacology and Physiology, Byrd Alzheimer's Center and Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612 USA.ORCID 0000-0003-1454-2719
Matthew P HoffmanMatrix and Morphogenesis Section, National Institute of Dental and Craniofacial Research, NIH, DHHS, Bethesda, MD 20892, USA.ORCID 0000-0002-8293-5998
Marla GearingDepartment of Pathology and Laboratory Medicine and Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0002-1959-7412
Jian LiuDivision of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA.ORCID 0000-0001-8552-1400
University of North Carolina at Chapel Hill · USRensselaer Polytechnic Institute · USNational Institute of Dental and Craniofacial Research · USNational Institutes of Health · USUnited Therapeutics (United States) · USUSF Health Byrd Alzheimer's Institute · USEmory University · US
Funding
The Goizueta Alzheimer's Disease Research CenterP30AG066511 · NIA · EMORY UNIVERSITY · PI ALLAN I LEVEY · 2020 to 2026
$29.0MGrowth Factor/Extracellular Matrix Interactions During Branching MorphogenesisZIADE000707 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI HOFFMAN, MATTHEW · 2009 to 2023
$14.0MCrystallographic studies of macromolecular structuresZICES102645 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PEDERSEN, LARS · 2018 to 2025
$12.6MCrystallographic studies of macromolecular structuresZIAES102645 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PEDERSEN, LARS · 2009 to 2017
$9.4MIn vitro synthesis of recombinant heparan sulfateR01HL094463 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, JIAN, PAWLINSKI, RAFAL L · 2009 to 2021
$5.2MHeparan Sulfate 3-O-Sulfation in Transcellular Propagation of Tauopathy in Alzheimer's DiseaseRF1AG069039 · NIA · RENSSELAER POLYTECHNIC INSTITUTE · PI LINHARDT, ROBERT J, LIU, JIAN · 2020 to 2020
$2.6MHeparan Sulfate in Prostate CancerU01CA225784 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI CAI, HOUJIAN, WANG, LIANCHUN · 2018 to 2023
$2.6MStructural Mechanisms of Hedgehog Autoprocessing in Physiology and DiseaseR01CA206592 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI CALLAHAN, BRIAN PATRICK, WANG, CHUNYU · 2017 to 2021
$2.0MDevelopment of analytical methods for glycosaminoglycans from biological sourcesR44GM142304 · NIGMS · GLYCAN THERAPEUTICS CORPORATION · PI WANG, ZHANGJIE · 2022 to 2023
$2.0MGrowth Factor/Extracellular Matrix Interactions During Branching MorphogenesisZ01DE000707 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI HOFFMAN, MATTHEW P · 2004 to 2008
$1.8MHeparan sulfate proteoglycan in the brain vascular clearance of amyloid-β and Alzheimer's diseaseRF1AG074289 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI WANG, LIANCHUN · 2021 to 2021
$1.8MHeparan sulfate proteoglycan in the brain vascular clearance of amyloid-β and Alzheimer's diseaseR01AG074289 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI WANG, LIANCHUN · 2024 to 2025
$1.2MIntramural NIH HHS Z01 DE000707Intramural NIH HHS ZIA ES102645NCI NIH HHS R01 CA206592NCI NIH HHS U01 CA225784NHLBI NIH HHS R01 HL094463NHLBI NIH HHS R01 HL144970NIA NIH HHS P30 AG066511NIA NIH HHS R01 AG069039NIA NIH HHS R01 AG074289NIA NIH HHS R56 AG062344NIA NIH HHS RF1 AG069039NIA NIH HHS RF1 AG074289NIA NIH HHS T32 AG078123NIGMS NIH HHS R21 GM143507NIGMS NIH HHS R43 GM140693NIGMS NIH HHS R43 GM142304NIGMS NIH HHS R43 GM149008NIGMS NIH HHS R44 GM142304
Abstract
PubMed holds no abstract for this paper.
Indexed as
Alzheimer DiseaseAnimalsBrainChromatography, LiquidHeparan SulfateMiceMice, KnockoutSulfatesSulfotransferasesTandem Mass SpectrometryHeparan SulfateSulfatesSulfotransferases
Identifiers
What Socratic holds
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LicenceCC BY-NC
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.