Evidence map›Paper›PMID 37237531›Full record

ArticleBiology2023

Metabolically Healthy Obesity Is a Misnomer: Components of the Metabolic Syndrome Linearly Increase with BMI as a Function of Age and Gender.

Yonit Marcus, Elad Segev, Gabi Shefer, David Eilam, Galina Shenkerman, Assaf Buch, Shani Shenhar-Tsarfaty, David Zeltser, Itzhak Shapira, Shlomo Berliner and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. The Metabolic Syndrome, a Human Disease.International journal of molecular sciences · 2024
    Review
  8. Update on Obesity in Psoriasis Patients.Life (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yonit MarcusThe Sagol Center for Epigenetics of Metabolism and Aging, Sourasky Medical Center, Tel Aviv 6423906, Israel.
Elad SegevThe Sagol Center for Epigenetics of Metabolism and Aging, Sourasky Medical Center, Tel Aviv 6423906, Israel.ORCID 0000-0002-2786-324X
Gabi SheferThe Sagol Center for Epigenetics of Metabolism and Aging, Sourasky Medical Center, Tel Aviv 6423906, Israel.ORCID 0000-0002-9243-509X
David EilamSchool of Zoology, George S. Wise Faculty of Life-Sciences, Tel-Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0002-4494-6928
Galina ShenkermanInstitute of Endocrinology, Metabolism and Hypertension, Tel-Aviv-Sourasky Medical Center, Tel Aviv 6423906, Israel.
Assaf BuchThe Sagol Center for Epigenetics of Metabolism and Aging, Sourasky Medical Center, Tel Aviv 6423906, Israel.ORCID 0000-0002-4412-6532
Shani Shenhar-TsarfatyDepartments of Medicine and Preventive Medicine, Tel Aviv-Sourasky Medical Center, Tel Aviv 6423906, Israel.
David ZeltserSackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Itzhak ShapiraSackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Shlomo BerlinerDepartments of Medicine and Preventive Medicine, Tel Aviv-Sourasky Medical Center, Tel Aviv 6423906, Israel.
Ori RogowskiSackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Tel Aviv Sourasky Medical Center · ILTel Aviv University · ILHolon Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to examine the relationships between body mass index (BMI) and metabolic syndrome (MS) components as a function of age and gender across weight categories.

methodsThis cross-sectional study included 19,328 subjects who participated in a health-screening program. We analyzed 14,093 apparently healthy subjects with a BMI ≥ 18.5 kg/m

resultsAt a BMI of 18.5 kg/m

conclusions(A) MS components increase linearly with BMI from the lowest normal BMI and continue to increase with age and BMI; (B) metabolically healthy obesity is rare in subjects with a high BMI and declines with age; (C) hypertension is the most common component in men; and (D) in women, MS components are seen at older ages than in men for the same BMI. Metabolic health declines with age and BMI in nearly all subjects with obesity.

Indexed as

hypertensionmetabolically healthy obesitymetabolic syndromenormometabolic obesityobesity

Identifiers

PMID37237531
PMCPMC10215588
OpenAlexW4376644222

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.