Evidence map›Paper›PMID 37237884›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress.

Wenji Ren, Zixu Wang, Jing Cao, Yulan Dong, Tuanjie Wang, Yaoxing Chen

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wenji RenDepartment of Animal Anatomy and Histoembryology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Zixu WangDepartment of Animal Anatomy and Histoembryology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Jing CaoDepartment of Animal Anatomy and Histoembryology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Yulan DongDepartment of Animal Anatomy and Histoembryology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Tuanjie WangChina Institute of Veterinary Drug Control, Beijing 100081, China.
Yaoxing ChenDepartment of Animal Anatomy and Histoembryology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-2576-5977
China Agricultural University · CNChina Institute of Veterinary Drug Control · CN

Funding

Beijing Natural Science Foundation 6222019National Natural Science Foundation of China 31873000National Natural Science Foundation of China 32172801
6 · The paper itself

Abstract

Excessive illumination is one of the most severe environmental factors that impacts the organism. There is growing evidence that obesity significantly contributes to the onset of chronic kidney disease. However, the effect of continuous light on the kidney and which color can produce an apparent phenomenon remains elusive. In this study, C57BL/6 mice given either a normal diet (LD-WN) or a high-fat diet (LD-WF) were subjected to a light cycle of 12 h of illumination followed by 12 h of darkness for 12 weeks. Meanwhile, 48 high-fat diet mice were given a 24 h monochromatic light exposure of varying colors (white, LL-WF; blue, LL-BF; green, LL-GF) for 12 weeks. As expected, the LD-WF mice showed significant obesity, kidney injury, and renal dysfunction compared with the LD-WN group. LL-BF mice had worse kidney injury than LD-WF mice, including higher

Indexed as

corticosteronehigh-fat dietinflammationkidneymonochromatic lightoxidative stress

Identifiers

PMID37237884
PMCPMC10215342
OpenAlexW4367316768

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.