Evidence mapPaperPMID 37237992Full record

ReviewAntioxidants (Basel, Switzerland)2023

Oxidative Stress, Reductive Stress and Antioxidants in Vascular Pathogenesis and Aging.

Mitko Mladenov, Lubomir Lubomirov, Olaf Grisk, Dimiter Avtanski, Vadim Mitrokhin, Iliyana Sazdova, Milena Keremidarska-Markova, Yana Danailova, Georgi Nikolaev, Rossitza Konakchieva and 1 more

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. The Role of the Gut Microbiota in Vascular Physiology and Health.International journal of molecular sciences · 2025
    Review
  16. Review
  17. Cocoa Shell Extract Restores Redox Balance in Developmental Hypertension in Male Rats: Roles of Nrf2, SOD2 and p-eNOS.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  18. Article
  19. Protective Effect ofJournal of microbiology and biotechnology · 2025
    Article
  20. Food science & nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mitko MladenovFaculty of Natural Sciences and Mathematics, Institute of Biology, "Ss. Cyril and Methodius" University, P.O. Box 162, 1000 Skopje, North Macedonia.ORCID 0000-0003-3475-2131
Lubomir LubomirovInstitute of Physiology, Brandenburg Medical School Theodor Fontane, 16816 Neuruppin, Germany.
Olaf GriskInstitute of Physiology, Brandenburg Medical School Theodor Fontane, 16816 Neuruppin, Germany.ORCID 0000-0001-6842-1256
Dimiter AvtanskiFriedman Diabetes Institute, Lenox Hill Hospital, Northwell Health, 110 E 59th Street, New York, NY 10003, USA.ORCID 0000-0002-4479-6448
Vadim MitrokhinDepartment of Physiology, Pirogov Russian National Research Medical University, 1 Ostrovityanova Street, 117997 Moscow, Russia.
Iliyana SazdovaDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.
Milena Keremidarska-MarkovaDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0001-9385-6593
Yana DanailovaDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.
Georgi NikolaevDepartment of Cell and Developmental Biology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.
Rossitza KonakchievaDepartment of Cell and Developmental Biology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0001-7981-4506
Hristo GagovDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tzankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0002-2759-7981

Funding

The Scientific Research Fund of the Ministry of Education and Science of Bulgaria KP-06-OPR03/18 from 19.12.2018.
6 · The paper itself

Abstract

This review is focused on the mechanisms that regulate health, disease and aging redox status, the signal pathways that counteract oxidative and reductive stress, the role of food components and additives with antioxidant properties (curcumin, polyphenols, vitamins, carotenoids, flavonoids, etc.), and the role of the hormones irisin and melatonin in the redox homeostasis of animal and human cells. The correlations between the deviation from optimal redox conditions and inflammation, allergic, aging and autoimmune responses are discussed. Special attention is given to the vascular system, kidney, liver and brain oxidative stress processes. The role of hydrogen peroxide as an intracellular and paracrine signal molecule is also reviewed. The cyanotoxins β-

Indexed as

agingantiallergicanti-inflammatorycurcumincyanotoxinsirisinmelatoninmitochondriaNADPH oxidaseROS signaling

Identifiers

PMID37237992
PMCPMC10215600

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.