Evidence mapPaperPMID 37238639Full record

ArticleBiomolecules2023

β-Glucan and Fatty Acid Based Mucoadhesive Carrier for Gastrointestinal Tract Specific Local and Sustained Drug Delivery.

Stephanie Vargas Esquivel, Himanshu N Bhatt, Rimpy Diwan, Ahsan Habib, Wen-Yee Lee, Zehedina Khatun, Md Nurunnabi

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Stephanie Vargas EsquivelAerospace Center (cSETR), University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0009-0000-7747-8908
Himanshu N BhattDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Texas at El Paso, El Paso, TX 79902, USA.
Rimpy DiwanDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Texas at El Paso, El Paso, TX 79902, USA.
Ahsan HabibDepartment of Chemistry and Biochemistry, College of Science, University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0003-3563-4276
Wen-Yee LeeDepartment of Chemistry and Biochemistry, College of Science, University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0002-1568-5546
Zehedina KhatunDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Texas at El Paso, El Paso, TX 79902, USA.
Md NurunnabiAerospace Center (cSETR), University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0003-4457-3401
The University of Texas at El Paso · US

Funding

NIH HHS R03OD032624
6 · The paper itself

Abstract

The oral route is considered the most convenient route of drug administration for both systemic and local delivery. Besides stability and transportation, another unmet but important issue regarding oral medication is retention duration within the specific region of the gastrointestinal (GI) tract. We hypothesize that an oral vehicle that can adhere and maintain retention within the stomach for a longer duration can be more effective to treat stomach-related diseases. Therefore, in this project, we developed a carrier that is highly specific to the stomach and maintains its retention for a longer duration. We developed a vehicle composed of β-

Indexed as

beta-GlucansFatty AcidsAnimalsDocosahexaenoic AcidsDrug CarriersDrug Delivery SystemsGastrointestinal TractMicebeta-GlucansDocosahexaenoic AcidsDrug CarriersFatty Acidslocal deliverymucoadhesiveoral medicinestomach specificβ-glucan

Identifiers

PMID37238639
PMCPMC10216773
OpenAlexW4367319398

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.