Evidence map›Paper›PMID 37238959›Full record

ArticleBiomedicines2023

The Effects of Alcohol Intoxication and Withdrawal on Hypothalamic Neurohormones and Extrahypothalamic Neurotransmitters.

Balázs Simon, András Buzás, Péter Bokor, Krisztina Csabafi, Katalin Eszter Ibos, Éva Bodnár, László Török, Imre Földesi, Andrea Siska, Zsolt Bagosi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Balázs SimonDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
András BuzásDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
Péter BokorDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
Krisztina CsabafiDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
Katalin Eszter IbosDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
Éva BodnárDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
László TörökDepartment of Traumatology, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.
Imre FöldesiInstitute of Laboratory Medicine, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.
Andrea SiskaInstitute of Laboratory Medicine, Albert Szent-Györgyi Medical School, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-2252-7095
Zsolt BagosiDepartment of Pathophysiology, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 1, 6720 Szeged, Hungary.
University of Szeged · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to determine the effects of alcohol intoxication and withdrawal on hypothalamic neurohormones such as corticotropin-releasing factor (CRF) and arginine vasopressin (AVP), and extrahypothalamic neurotransmitters such as striatal dopamine (DA), amygdalar gamma aminobutyric acid (GABA), and hippocampal glutamate (GLU). In addition, the participation of the two CRF receptors, CRF1 and CRF2, was investigated. For this purpose, male Wistar rats were exposed to repeated intraperitoneal (ip) administration of alcohol every 12 h, for 4 days and then for 1 day of alcohol abstinence. On the fifth or sixth day, intracerebroventricular (icv) administration of selective CRF1 antagonist antalarmin or selective CRF2 antagonist astressin

Indexed as

alcohol intoxicationalcohol withdrawalAVPCRFdopamineGABAglutamate

Identifiers

PMID37238959
PMCPMC10215965
OpenAlexW4367321326

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.