Evidence map›Paper›PMID 37239884›Full record

ArticleInternational journal of molecular sciences2023

Can Pharmacogenetic Variants in

Marina Jelovac, Nikola Kotur, Bojan Ristivojevic, Djordje Pavlovic, Vesna Spasovski, Nemanja Damjanov, Sonja Pavlovic, Branka Zukic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Rapid Detection ofDrug design, development and therapy · 2024
    Article
  4. Impaired Regulation by IL-35 in Systemic Sclerosis.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Marina JelovacInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.ORCID 0000-0003-1344-7867
Nikola KoturInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.
Bojan RistivojevicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.ORCID 0000-0003-0600-7345
Djordje PavlovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.
Vesna SpasovskiInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.
Nemanja DamjanovInstitute of Rheumatology, 11000 Belgrade, Serbia.
Sonja PavlovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.
Branka ZukicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11000 Belgrade, Serbia.
University of Belgrade · RS

Funding

Ministry of Science, Technological Development and Innovation, Republic of Serbia 451-03-47/2023-01/ 200042
6 · The paper itself

Abstract

Systemic sclerosis (SSc) is a rare connective tissue disorder with highest morbidity and mortality among rheumatologic diseases. Disease progression is highly heterogeneous between patients, implying a strong need for individualization of therapy. Four pharmacogenetic variants, namely

Indexed as

Pharmacogenomic VariantsScleroderma, SystemicAzathioprineGenotypeHumansLiver-Specific Organic Anion Transporter 1MethotrexateMethylenetetrahydrofolate Reductase (NADPH2)Polymorphism, Single NucleotideAzathioprineLiver-Specific Organic Anion Transporter 1MethotrexateMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanSLCO1B1 protein, humanazathioprinemethotrexatepersonalized therapypharmacogenetics markersrheumatologic diseasessystemic sclerosis

Identifiers

PMID37239884
PMCPMC10217985
OpenAlexW4376138806

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.