Evidence mapPaperPMID 37240495Full record

ReviewJournal of clinical medicine2023

Understanding Progestins: From Basics to Clinical Applicability.

Manuel García-Sáenz, Raúl Ibarra-Salce, Francisco Javier Pozos-Varela, Tania Sofia Mena-Ureta, Susana Flores-Villagómez, Mario Santana-Mata, Ramón G De Los Santos-Aguilar, Daniel Uribe-Cortés, Aldo Ferreira-Hermosillo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Article
  3. Progestogen supplementation to prevent miscarriage: Evidence and controversies.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Combined Oral Contraceptives and the Risk of Thrombosis.International journal of molecular sciences · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Gut Bacteria Encode Reductases that Biotransform Steroid Hormones.bioRxiv : the preprint server for biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Manuel García-SáenzServicio de Endocrinología, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.ORCID 0000-0001-9216-0383
Raúl Ibarra-SalceDepartamento de Endocrinología, Facultad de Medicina, Universidad Autónoma de Coahuila, Saltillo 25204, Mexico.
Francisco Javier Pozos-VarelaHospital Star Médica, Aguascalientes 20029, Mexico.
Tania Sofia Mena-UretaHospital Star Médica, Aguascalientes 20029, Mexico.
Susana Flores-VillagómezCentro Médico Campestre, Leon 37180, Mexico.ORCID 0009-0001-2593-2520
Mario Santana-MataDepartamento de Medicina Interna, Hospital General de Zona N. 2, Saltillo 25296, Mexico.
Ramón G De Los Santos-AguilarDepartamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-7511-1050
Daniel Uribe-CortésHospital Ángeles Clinica Londres Torre Frontera, Mexico City 06700, Mexico.
Aldo Ferreira-HermosilloUnidad de Investigación Médica en Enfermedades Endocrinas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.ORCID 0000-0002-5159-9856
Hospital Médica Sur · MXMexican Social Security Institute · MXCentro Médico ABC · MXHospital Angeles Clinica Londres · MXHospital General De Zona · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXUniversidad Autónoma de Coahuila · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progestin is a term used to describe a synthetic progestogen. The activity and potency of synthetic progestins are mostly evaluated via parameters associated with their endometrial effects, which are related to their interactions with progesterone, estrogen, androgen, glucocorticoid, and mineralocorticoid receptors. The chemical structure of progestins is the key to understanding their interactions with these receptors and predicting the other effects associated with these drugs. Due to their endometrial effect, progestins are used for different gynecological conditions, such as endometriosis, contraception, hormonal replacement therapy, and artificial reproduction techniques. This review is focused on improving our knowledge of progestins (from their history and biochemical effects related to their chemical structures to clinical applications in gynecological conditions) in order to improve clinical practice.

Indexed as

contraceptive agentsendometriosishormone replacement therapyluteal phaseprogesterone congenersprogestinsprogestogens

Identifiers

PMID37240495
PMCPMC10218893
OpenAlexW4376138567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.