Evidence map›Paper›PMID 37240727›Full record

ArticleLife (Basel, Switzerland)2023

The rs2682826 Polymorphism of the

Leticia Perticarrara Ferezin, Cezar Kayzuka, Vitória Carolina Rondon Pereira, Murilo Ferreira de Andrade, Carlos Augusto Fernandes Molina, Silvio Tucci, Jose Eduardo Tanus-Santos, Riccardo Lacchini

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Leticia Perticarrara FerezinDepartment of Psychiatric Nursing and Human Sciences, Ribeirão Preto College of Nursing, University of Sao Paulo, Ribeirao Preto 14040-902, Brazil.
Cezar KayzukaDepartment of Pharmacology, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14049-902, Brazil.ORCID 0000-0002-5274-5886
Vitória Carolina Rondon PereiraDepartment of Pharmacology, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14049-902, Brazil.
Murilo Ferreira de AndradeDepartment of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Carlos Augusto Fernandes MolinaDepartment of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Silvio TucciDepartment of Surgery and Anatomy, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo 05508-090, Brazil.
Jose Eduardo Tanus-SantosDepartment of Pharmacology, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14049-902, Brazil.ORCID 0000-0002-9945-9633
Riccardo LacchiniDepartment of Psychiatric Nursing and Human Sciences, Ribeirão Preto College of Nursing, University of Sao Paulo, Ribeirao Preto 14040-902, Brazil.ORCID 0000-0002-3738-2036
Universidade de São Paulo · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior financial code 01National Council for Scientific and Technological Development 302898/2020-4São Paulo Research Foundation 2016/04449-0São Paulo Research Foundation 2018/18312-2
6 · The paper itself

Abstract

Erectile dysfunction (ED) is a common male disorder, often associated with cardiovascular disease and ageing. The Sildenafil, a PDE5 inhibitor, can improve the erectile function by prolonging the nitric oxide (NO) downstream effect. NO is a molecule of pivotal importance in erection physiology and is mainly produced by neuronal nitric oxide synthase (nNOS) and endothelial NO synthase (eNOS). While it has been shown that

Indexed as

erectile dysfunctionneuronal nitric oxide synthasenitric oxidepolymorphismrs13124532rs2389866rs2682826rs3733526rs41279104

Identifiers

PMID37240727
PMCPMC10221433
OpenAlexW4367053136

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.