A Pilot Study of Dietetic, Phenotypic, and Genotypic Features Influencing Hypertensive Disorders of Pregnancy in Women with Pregestational Diabetes Mellitus.
Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 5 institutions in 2 countries.
Karina Dos SantosPrograma de Pós-Graduação em Nutrição, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, 373-Bloco J 2° Andar, Cidade Universitária, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0003-4841-0554
Eliane Lopes RosadoPrograma de Pós-Graduação em Nutrição, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, 373-Bloco J 2° Andar, Cidade Universitária, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0003-0889-4662
Ana Carolina Proença da FonsecaLaboratório de Genética Humana, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Pavilhão Leônidas Deane, Avenida Brasil 4365, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0001-6123-0481
Gabriella Pinto BelfortPrograma de Pós-Graduação em Nutrição, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, 373-Bloco J 2° Andar, Cidade Universitária, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0003-2066-7446
Letícia Barbosa Gabriel da SilvaPrograma de Pós-Graduação em Nutrição, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, 373-Bloco J 2° Andar, Cidade Universitária, Rio de Janeiro 21941-902, Brazil.
Marcelo Ribeiro-AlvesInstituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil 4365, Rio de Janeiro 21040-360, Brazil.ORCID 0000-0002-8663-3364
Verônica Marques ZembrzuskiLaboratório de Genética Humana, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Pavilhão Leônidas Deane, Avenida Brasil 4365, Rio de Janeiro 21040-360, Brazil.
Mario CamposLaboratório de Genética Humana, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Pavilhão Leônidas Deane, Avenida Brasil 4365, Rio de Janeiro 21040-360, Brazil.
Lenita ZajdenvergDepartamento de Clínica Médica, Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, 373-Bloco K, 2° Andar, Cidade Universitária, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0002-1579-3299
Michele DrehmerPrograma de Pós-Graduação em Epidemiologia e Programa de Pós-Graduação em Alimentação, Nutrição e Saúde, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2400, Porto Alegre 90035-003, Brazil.
J Alfredo MartínezPrecision Nutrition and Cardiometabolic Health Program, IMDEA Food Institute (Instituto Madrileño de Estudos Avanzados en Alimentación), Crta. de Canto Blanco, n 8, E-28049 Madrid, Spain.
Cláudia SaundersPrograma de Pós-Graduação em Nutrição, Instituto de Nutrição Josué de Castro, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho, 373-Bloco J 2° Andar, Cidade Universitária, Rio de Janeiro 21941-902, Brazil.
Universidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BRInstituto Evandro Chagas · BRMadrid Institute for Advanced Studies · ESUniversidade Federal do Rio Grande do Sul · BR
Funding
Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/202.972/2016-6 and E-26/201.193/2021National Council for Scientific and Technological Development 409032/2016-6
6 · The paper itself
Abstract
Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and perinatal morbimortality. Dietetic, phenotypic, and genotypic factors influencing HDP were analyzed during a nutrigenetic trial in Rio de Janeiro, Brazil (2016-2020). Pregnant women with pregestational diabetes mellitus (n = 70) were randomly assigned to a traditional or DASH diet group. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured during prenatal visits and HDP were diagnosed using international criteria. Phenotypic data were obtained from medical records and personal interviews. Genotyping for FTO and ADRB2 polymorphisms used RT-PCR. Linear mixed-effect models and time-to-event analyses were performed. The variables with significant effect on the risk for progression to HDP were: black skin color (adjusted hazard ratio [aHR] 8.63,
Indexed as
DASH dietnutrigeneticspreeclampsiapregnancy in diabetespregnancy-induced hypertension
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
A Pilot Study of Dietetic, Phenotypic, and Genotypic Features Influencing Hypertensive Disorders of Pregnancy in Women with Pregestational Diabetes Mellitus. · full record | Socratic