Evidence map›Paper›PMID 37244654›Full record

ArticleAnalytica chimica acta2023

Pd@Pt nanoparticle-linked immunosorbent assay for quantification of Collagen type II.

Eunice Y Kwon, Haneen A Abusharkh, Xiaofan Ruan, Dan Du, Ellis Hammond-Pereira, Bernard J Van Wie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytica chimica acta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eunice Y KwonVoiland School of Chemical Engineering and Bioengineering, Washington State University, Pullman, WA, 99164-6515, United States.
Haneen A AbusharkhVoiland School of Chemical Engineering and Bioengineering, Washington State University, Pullman, WA, 99164-6515, United States.
Xiaofan RuanSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164-2920, United States.
Dan DuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164-2920, United States.
Ellis Hammond-PereiraVoiland School of Chemical Engineering and Bioengineering, Washington State University, Pullman, WA, 99164-6515, United States.
Bernard J Van WieVoiland School of Chemical Engineering and Bioengineering, Washington State University, Pullman, WA, 99164-6515, United States. Electronic address: bvanwie@wsu.edu.
Washington State University · US

Funding

TRAINING IN BIOTECHNOLOGY: EMPHASIS ON PROTEIN CHEMISTRYT32GM008336 · NIGMS · WASHINGTON STATE UNIVERSITY · PI CALL, DOUGLAS R. · 1989 to 2023
$8.9M
NIGMS NIH HHS T32 GM008336
6 · The paper itself

Abstract

The evaluation of specific protein content in engineered tissues provides a gateway for developing regenerative medicine treatments. Since collagen type II, the major component of articular cartilage, is critical for the blossoming field of articular cartilage tissue engineering, the interest in this protein is growing rapidly. Accordingly, the need for quantification of collagen type II is increasing as well. In this study, we provide recent results for a new quantifying nanoparticle sandwich immunoassay technique for collagen type II. Since mesoporous palladium@platinum (Pd@Pt) nanoparticles have peroxidase-like catalytic activities, these nanoparticles were utilized in an enzyme-linked immunosorbent assay (ELISA)-like format to circumvent the need for traditional enzymes. These nanoparticles were easily conjugated with anti-collagen type II antibodies by the natural affinity interaction and used to develop a direct sandwich ELISA-like format for nanoparticle-linked immunosorbent assays. Using this method, we obtained a limit of detection of 1 ng mL

Indexed as

ImmunosorbentsNanoparticlesCollagen Type IIEnzyme-Linked Immunosorbent AssayImmunoassayCollagen Type IIImmunosorbentsCollagen type IIELISA-like formatNanoparticle-linked immunosorbent assayPd@Pt nanoparticlePeroxidase-like catalytic activityPeroxidase-like nanoparticle

Identifiers

PMID37244654
PMCPMC10564550
OpenAlexW4366817774

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.