ArticleThe Journal of clinical endocrinology and metabolism2023
The Burden of Obesity in Type 1 Diabetic Subjects: A Sex-specific Analysis From the AMD Annals Initiative.
Article in The Journal of clinical endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Prevalence and biopsychosocial factors associated with overweight and obesity in adults with type 1 diabetes.International journal of obesity (2005) · 2026Article
- Magnitude and correlates of overweight or obesity among adults with diabetes mellitus duration of five or more years in rural Uganda: A cross-sectional study.Global epidemiology · 2026Article
- 8. Obesity and Weight Management for the Prevention and Treatment of Diabetes: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Trends in baseline HbA1c and body-mass index in randomised trials of people with type 1 diabetes from 1993 to 2025: an IMI2 SOPHIA systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Type 1 Diabetes Mellitus and Alexithymia: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Nutritional myths in adolescents and young adults with type 1 diabetes: a pilot study.BMC nutrition · 2025Article
- Lights and Shadows of Bariatric Surgery: Insights from a Nationwide Administrative Database of People Living with Type 1 Diabetes and Obesity.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025Article
- Metabolic health in people living with type 1 diabetes in Belgium: a repeated cross-sectional study.Diabetologia · 2024Article
- Temporal trends in the starting of insulin therapy in type 2 diabetes in Italy: data from the AMD Annals initiative.Journal of endocrinological investigation · 2024Article
- Trend of pregnancy outcomes in type 1 diabetes compared to control women: a register-based analysis in 1996-2018.Frontiers in endocrinology · 2023Article
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Authors and funding
15 authors at 10 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveObesity is a growing emergency in type 1 diabetes (T1D). Sex differences in obesity prevalence and its clinical consequences in adult T1D subjects have been poorly investigated. The aim of this study was to investigate the prevalence of obesity and severe obesity, clinical correlates, and potential sex differences in a large cohort of T1D subjects participating to the AMD (Associazione Medici Diabetologi) Annals Initiative in Italy. RESEARCH DESIGN AND
methodsThe prevalence of obesity [body mass index(BMI) ≥30 kg/m2] and severe obesity (BMI ≥ 35 kg/m2) according to sex and age, as well as obesity-associated clinical variables, long-term diabetes complications, pharmacological treatment, process indicators and outcomes, and overall quality of care (Q-score) were evaluated in 37 436 T1D subjects (45.3% women) attending 282 Italian diabetes clinics during 2019.
resultsOverall, the prevalence of obesity was similar in the 2 sexes (13.0% in men and 13.9% in women; mean age 50 years), and it increased with age, affecting 1 out of 6 subjects ages >65 years. Only severe obesity (BMI >35 kg/m2) was more prevalent among women, who showed a 45% higher risk of severe obesity, compared with men at multivariate analysis. Cardiovascular disease risk factors (lipid profile, glucose, and blood pressure control), and the overall quality of diabetes care were worse in obese subjects, with no major sex-related differences. Also, micro- and macrovascular complications were more frequent among obese than nonobese T1D men and women.
conclusionsObesity is a frequent finding in T1D adult subjects, and it is associated with a higher burden of cardiovascular disease risk factors, micro- and macrovascular complications, and a lower quality of care, with no major sex differences. T1D women are at higher risk of severe obesity.
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